ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene SymbolGene NameEnsemble IDStatusUniProt IDStructure Visualization
Arl6ip4ADP-ribosylation factor-like 6 interacting protein 4ENSMUSG00000029404protein-codingAR6P4_MOUSEAlphaFold
Function: Involved in modulating alternative pre-mRNA splicing with either 5' distal site activation or preferential use of 3' proximal site. {ECO:0000250}.
Subcellular Location: Nucleus, nucleolus {ECO:0000250}. Nucleus speckle {ECO:0000250}.

BloodBrainHeartLiverLungAsBPA10mgBPA10ugDEHPPM2.5(CHI)PM2.5(JHK)PbTBTTCDDBloodBrainHeartLiverLungBloodLiver
−0.6−0.4−0.200.20.40.6Fold Change3 Weeks20 Weeks40 WeeksMale
BloodBrainHeartLiverLungAsBPA10mgBPA10ugDEHPPM2.5(CHI)PM2.5(JHK)PbTBTTCDDBloodBrainHeartLiverLungBloodLiver
−0.6−0.4−0.200.20.40.6Fold Change3 Weeks20 Weeks40 WeeksFemale

Expression of "Arl6ip4"gene in different tissues
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TBTTCDD20304050
3 Weeks20 Weeks40 WeeksCPMFemale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TBTTCDD20304050
3 Weeks20 Weeks40 WeeksLiverMale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TCDDTBT10203040
3 Weeks20 Weeks40 WeeksCPMFemale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TCDDTBT10203040
3 Weeks20 Weeks40 WeeksBloodMale
CtrlPM2.5(CHI)304050
3 Weeks20 WeeksCPMFemale
CtrlPM2.5(CHI)304050
3 Weeks20 WeeksLungMale
CtrlPM2.5(CHI)0102030
Female
0102030
HeartMale
BPA10mgBPA10ugCtrl202530
Female
BPA10mgBPA10ugCtrl202530
BrainMale




Tools:
Viewing a 37.1 Kb region in 920px, 1 pixel spans 40 bp
  • Sample

refGene

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gencodeM19Basic

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Ruler

chr5
qF124080K124090K124100K124110K124120K124130K124140K124150K124160K124170K124180K

3 Weeks Female Liver (Ctrl)

1.00.0
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3 Weeks Male Liver (Ctrl)

1.00.0
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20 Weeks Female Blood (Ctrl)

1.00.0
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20 Weeks Male Blood (Ctrl)

1.00.0
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20 Weeks Female Brain (Ctrl)

1.00.0
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20 Weeks Male Brain (Ctrl)

1.00.0
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20 Weeks Female Liver (Ctrl)

1.00.0
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20 Weeks Male Liver (Ctrl)

1.00.0
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DAR Position

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OCR Position

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OCR associated with "Arl6ip4" gene

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OCR
Position
Distance to TSS
Differential accessibility
Annotation
1chr5:124115924-12411641461NOpromoter-TSS (NM_144509)
2chr5:124118696-1241191332807NOTTS (NM_144509)
3chr5:124119819-1241200113807NO3' UTR (NM_011256, exon 25 of 25)
4chr5:124120092-1241204474162NO3' UTR (NM_011256, exon 25 of 25)
5chr5:124120893-1241213255001NO3' UTR (NM_011256, exon 25 of 25)
6chr5:124138075-12413847922169YESintron (NM_001289472, intron 5 of 24)
7chr5:124148677-12414907032766NOintron (NM_001289472, intron 2 of 24)


Exposure induced DNA methylation change