ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene SymbolGene NameEnsemble IDStatusUniProt IDStructure Visualization
Baiap2brain-specific angiogenesis inhibitor 1-associated protein 2ENSMUSG00000025372protein-codingQ3UKP6_MOUSEAlphaFold
Function: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions. {ECO:0000256|ARBA:ARBA00025545}.
Subcellular Location: Cell projection, filopodium {ECO:0000256|ARBA:ARBA00004486}. Cell projection, ruffle {ECO:0000256|ARBA:ARBA00004466}. Cytoplasm, cytoskeleton {ECO:0000256|ARBA:ARBA00004245}. Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.

Expression of "Baiap2"gene in different tissues






OCR associated with "Baiap2" gene

OCRPositionDistance to TSSDifferential accessibilityAnnotation
1chr11:119928311-119928667-14603YESintron (NR_039557, intron 2 of 2)
2chr11:119933851-119934375-8979NOIntergenic
3chr11:119935553-119935713-7459YESIntergenic
4chr11:119936591-119937167-6213NOIntergenic
5chr11:119938775-119939476-3966NOIntergenic
6chr11:119942374-119943509-150NOpromoter-TSS (NM_001037754)
7chr11:119945235-1199455802316NOintron (NM_130862, intron 1 of 13)
8chr11:119947458-1199478164545NOintron (NM_130862, intron 1 of 13)
9chr11:119948726-1199491195831NOintron (NM_130862, intron 1 of 13)
10chr11:119952488-1199527749539NOintron (NM_130862, intron 1 of 13)
11chr11:119953594-11995377510593NOintron (NM_130862, intron 1 of 13)
12chr11:119954300-11995458811352NOintron (NM_130862, intron 1 of 13)
13chr11:119955013-11995579312311YESintron (NM_130862, intron 1 of 13)
14chr11:119959008-11995917816001NOintron (NM_130862, intron 2 of 13)
15chr11:119961544-11996181618588YESintron (NM_130862, intron 3 of 13)
16chr11:119967750-11996820824887YESintron (NM_130862, intron 3 of 13)
17chr11:119969848-11997044927057NOintron (NM_130862, intron 3 of 13)
18chr11:119973864-11997410730894NOintron (NM_130862, intron 3 of 13)
19chr11:119976132-11997658533267NOintron (NM_130862, intron 3 of 13)



Exposure induced DNA methylation change