ToxiTaRGET

ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene Symbol	Gene Name	Ensemble ID	Status	UniProt ID	Structure Visualization
Cnih4	cornichon family AMPA receptor auxiliary protein 4	ENSMUSG00000062169	protein-coding	CNIH4_MOUSE	AlphaFold

Function: Involved in G protein-coupled receptors (GPCRs) trafficking from the endoplasmic reticulum to the cell surface; it promotes the exit of GPCRs from the early secretory pathway, likely through interaction with the COPII machinery. {ECO:0000250|UniProtKB:Q9P003}.
Subcellular Location: Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9P003}. Endoplasmic reticulum-Golgi intermediate compartment {ECO:0000250|UniProtKB:Q9P003}.

Expression of "Cnih4"gene in different tissues

OCR associated with "Cnih4" gene

OCR	Position	Distance to TSS	Differential accessibility	Annotation
1	chr1:181150659-181151476	137	NO	intron (NM_030131, intron 1 of 4)
2	chr1:181168501-181168942	17791	NO	3' UTR (NM_030131, exon 5 of 5)
3	chr1:181170153-181170664	19478	NO	Intergenic

Gene information

Exposure induced expression change

Gene expression across exposure

Expression of "Cnih4"gene in different tissues

Exposure induced chromatin accessibility change

OCR associated with "Cnih4" gene

Exposure induced DNA methylation change