ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene SymbolGene NameEnsemble IDStatusUniProt IDStructure Visualization
Dynll2dynein light chain LC8-type 2ENSMUSG00000020483protein-codingDYL2_MOUSEAlphaFold
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). {ECO:0000250}.
Subcellular Location: Cytoplasm, cytoskeleton {ECO:0000269|PubMed:14561217}.

Expression of "Dynll2"gene in different tissues





OCR associated with "Dynll2" gene

OCRPositionDistance to TSSDifferential accessibilityAnnotation
1chr11:88015214-88015562-17090NOIntergenic
2chr11:88012739-88012994-14569NOIntergenic
3chr11:88009620-88010135-11580YESIntergenic
4chr11:87991848-87992213-4498NOintron (NM_001168471, intron 1 of 2)
5chr11:87986910-87987822167NOpromoter-TSS (NM_001168472)
6chr11:87984616-879848961829NOintron (NM_001168471, intron 1 of 2)
7chr11:87978693-879791237677NOTTS (NM_001168472)
8chr11:87977072-879774499324NOIntergenic
9chr11:87975826-8797612810608YESIntergenic
10chr11:87974752-8797518911614YESIntergenic
11chr11:87968828-8796904917646NOIntergenic
12chr11:87967684-8796803018728NOIntergenic
13chr11:87966215-8796640920273YESIntergenic
14chr11:87965374-8796568421056YESIntergenic
15chr11:87964518-8796472021966NOIntergenic
16chr11:87955233-8795543831249YESIntergenic


Exposure induced DNA methylation change