ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene SymbolGene NameEnsemble IDStatusUniProt IDStructure Visualization
Gm15832ring finger protein 149ENSMUSG00000048234protein-codingRN149_MOUSEAlphaFold
Function: E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation. {ECO:0000250}.
Subcellular Location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

BloodBrainHeartLiverLungAsBPA10mgBPA10ugDEHPPM2.5(CHI)PM2.5(JHK)PbTBTTCDDBloodBrainHeartLiverLungBloodLiver
−1.5−1−0.500.511.5Fold Change3 Weeks20 Weeks40 WeeksMale
BloodBrainHeartLiverLungAsBPA10mgBPA10ugDEHPPM2.5(CHI)PM2.5(JHK)PbTBTTCDDBloodBrainHeartLiverLungBloodLiver
−1.5−1−0.500.511.5Fold Change3 Weeks20 Weeks40 WeeksFemale

Expression of "Gm15832"gene in different tissues
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TBTTCDD0123456
3 Weeks20 Weeks40 WeeksCPMFemale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TBTTCDD0123456
3 Weeks20 Weeks40 WeeksLiverMale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TCDDTBT51015
3 Weeks20 Weeks40 WeeksCPMFemale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TCDDTBT51015
3 Weeks20 Weeks40 WeeksBloodMale
CtrlPM2.5(CHI)12345
3 Weeks20 WeeksCPMFemale
CtrlPM2.5(CHI)12345
3 Weeks20 WeeksLungMale
CtrlPM2.5(CHI)−0.500.511.5
Female
−0.500.511.5
HeartMale
BPA10mgBPA10ugCtrl012
Female
BPA10mgBPA10ugCtrl012
BrainMale