ToxiTaRGET

ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene Symbol	Gene Name	Ensemble ID	Status	UniProt ID	Structure Visualization
Gnl3	guanine nucleotide binding protein-like 3 (nucleolar)	ENSMUSG00000042354	protein-coding	GNL3_MOUSE	AlphaFold

Function: May be required to maintain the proliferative capacity of stem cells (By similarity). Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation. {ECO:0000250, ECO:0000269|PubMed:21132010}.
Subcellular Location: Nucleus {ECO:0000269|PubMed:21132010}. Nucleus, nucleolus {ECO:0000269|PubMed:12464630}. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}.

Gene information

Exposure induced expression change

Gene expression across exposure

Expression of "Gnl3"gene in different tissues

Exposure induced chromatin accessibility change