ToxiTaRGET

ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene Symbol	Gene Name	Ensemble ID	Status	UniProt ID	Structure Visualization
Haus8	4HAUS augmin-like complex, subunit 8	ENSMUSG00000035439	protein-coding	HAUS8_MOUSE	AlphaFold

Function: Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000250}.
Subcellular Location: Cytoplasm {ECO:0000250|UniProtKB:Q9BT25}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9BT25}. Cytoplasm, cytoskeleton, spindle {ECO:0000250|UniProtKB:Q9BT25}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000250|UniProtKB:Q9BT25}. Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively. Localizes to mitotic spindle microtubules (By similarity). {ECO:0000250|UniProtKB:Q9BT25}.

Expression of "Haus8"gene in different tissues

OCR associated with "Haus8" gene

OCR	Position	Distance to TSS	Differential accessibility	Annotation
1	chr8:71256616-71256909	15827	YES	intron (NM_001163042, intron 4 of 10)

Gene information

Exposure induced expression change

Gene expression across exposure

Expression of "Haus8"gene in different tissues

Exposure induced chromatin accessibility change

OCR associated with "Haus8" gene

Exposure induced DNA methylation change