ToxiTaRGET

ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene Symbol	Gene Name	Ensemble ID	Status	UniProt ID	Structure Visualization
Tfcp2	transcription factor CP2	ENSMUSG00000009733	protein-coding	TFCP2_MOUSE	AlphaFold

Function: Binds a variety of cellular promoters including fibrinogen, alpha-globin promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter (By similarity). {ECO:0000250}.
Subcellular Location: Nucleus {ECO:0000250}.

Expression of "Tfcp2"gene in different tissues

OCR associated with "Tfcp2" gene

OCR	Position	Distance to TSS	Differential accessibility	Annotation
1	chr15:100551356-100552311	174	YES	intron (NM_033476, intron 1 of 15)
2	chr15:100537991-100538233	13896	YES	intron (NM_033476, intron 2 of 15)
3	chr15:100531100-100531714	20601	NO	intron (NM_033476, intron 2 of 15)

Gene information

Exposure induced expression change

Gene expression across exposure

Expression of "Tfcp2"gene in different tissues

Exposure induced chromatin accessibility change

OCR associated with "Tfcp2" gene

Exposure induced DNA methylation change