ToxiTaRGET Database of Toxicant Exposures and Responses

Gene information

Gene SymbolGene NameEnsemble IDStatusUniProt IDStructure Visualization
Ttc30btetratricopeptide repeat domain 30BENSMUSG00000075273protein-codingB2RXA2_MOUSEAlphaFold
Function: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip. {ECO:0000256|ARBA:ARBA00002105, ECO:0000256|RuleBase:RU367070}.
Subcellular Location: Cell projection, cilium {ECO:0000256|ARBA:ARBA00004138, ECO:0000256|RuleBase:RU367070}.

BloodBrainHeartLiverLungAsBPA10mgBPA10ugDEHPPM2.5(CHI)PM2.5(JHK)PbTBTTCDDBloodBrainHeartLiverLungBloodLiver
−0.500.5Fold Change3 Weeks20 Weeks40 WeeksMale
BloodBrainHeartLiverLungAsBPA10mgBPA10ugDEHPPM2.5(CHI)PM2.5(JHK)PbTBTTCDDBloodBrainHeartLiverLungBloodLiver
−0.500.5Fold Change3 Weeks20 Weeks40 WeeksFemale

Expression of "Ttc30b"gene in different tissues
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TBTTCDD46810
3 Weeks20 Weeks40 WeeksCPMFemale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TBTTCDD46810
3 Weeks20 Weeks40 WeeksLiverMale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TCDDTBT01234
3 Weeks20 Weeks40 WeeksCPMFemale
AsBPA10mgBPA10ugCtrlDEHPPbPM2.5(CHI)PM2.5(JHK)TCDDTBT01234
3 Weeks20 Weeks40 WeeksBloodMale





Tools:
Viewing a 50.8 Kb region in 920px, 1 pixel spans 55 bp
  • Sample

refGene

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gencodeM19Basic

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Ruler

chr2
qC375840K75850K75860K75870K75880K75890K75900K75910K75920K75930K75940K75950K75960K75970K75980K75990K

3 Weeks Female Liver (Ctrl)

1.00.0
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3 Weeks Male Liver (Ctrl)

1.00.0
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20 Weeks Female Blood (Ctrl)

1.00.0
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20 Weeks Male Blood (Ctrl)

1.00.0
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20 Weeks Female Brain (Ctrl)

1.00.0
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20 Weeks Male Brain (Ctrl)

1.00.0
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20 Weeks Female Liver (Ctrl)

1.00.0
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20 Weeks Male Liver (Ctrl)

1.00.0
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DAR Position

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OCR Position

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OCR associated with "Ttc30b" gene

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OCR
Position
Distance to TSS
Differential accessibility
Annotation
1chr2:75937898-75938785120NOexon (NM_028235, exon 1 of 1)
2chr2:75930787-759312887424YES3' UTR (NM_172666, exon 20 of 20)
3chr2:75907252-7590743631118NOintron (NM_172666, intron 17 of 19)
4chr2:75892007-7589236046278YESintron (NM_172666, intron 13 of 19)



Exposure induced DNA methylation change