ToxiTaRGET

As BPA10mg BPA10ug DEHP Pb PM2.5(JHK) PM2.5(CHI) TBT TCDD

Table1. Number of differentially down-regulated gene in 20 weeks male liver under TCDD exposure.

No.	Gene	Exposure	Sex	Age	Tissue	Fold-change	DEG
1	Pdia4	TCDD	Male	20Weeks	liver	-0.585886406928743	Down-regulated
2	Tjp3	TCDD	Male	20Weeks	liver	-0.587624953218873	Down-regulated
3	Gm36028	TCDD	Male	20Weeks	liver	-0.589428473336482	Down-regulated
4	Ugt2b1	TCDD	Male	20Weeks	liver	-0.59033257259031	Down-regulated
5	Pop1	TCDD	Male	20Weeks	liver	-0.592076967611113	Down-regulated
6	Fbxl19	TCDD	Male	20Weeks	liver	-0.59264023659295	Down-regulated
7	Gstp1	TCDD	Male	20Weeks	liver	-0.593353150056126	Down-regulated
8	AC132455.2	TCDD	Male	20Weeks	liver	-0.594528783152134	Down-regulated
9	Gm40264	TCDD	Male	20Weeks	liver	-0.59821118022082	Down-regulated
10	Zc2hc1c	TCDD	Male	20Weeks	liver	-0.59859493419232	Down-regulated
11	Tbc1d8	TCDD	Male	20Weeks	liver	-0.607404702139685	Down-regulated
12	Abca8a	TCDD	Male	20Weeks	liver	-0.611083091620849	Down-regulated
13	Tmie	TCDD	Male	20Weeks	liver	-0.615705236619361	Down-regulated
14	Lgals4	TCDD	Male	20Weeks	liver	-0.616664807714982	Down-regulated
15	Gm10734	TCDD	Male	20Weeks	liver	-0.616931299172539	Down-regulated
16	Serpinb6b	TCDD	Male	20Weeks	liver	-0.62399101927269	Down-regulated
17	Alg12	TCDD	Male	20Weeks	liver	-0.624269567383709	Down-regulated
18	Gsta4	TCDD	Male	20Weeks	liver	-0.62496982879163	Down-regulated
19	Ppid	TCDD	Male	20Weeks	liver	-0.625143203508815	Down-regulated
20	Gon7	TCDD	Male	20Weeks	liver	-0.625990019158411	Down-regulated
21	C630043F03Rik	TCDD	Male	20Weeks	liver	-0.632025758179258	Down-regulated
22	Banp	TCDD	Male	20Weeks	liver	-0.633664883865785	Down-regulated
23	Zfp518a	TCDD	Male	20Weeks	liver	-0.634876327064015	Down-regulated
24	Nid2	TCDD	Male	20Weeks	liver	-0.638632455968103	Down-regulated
25	Ahsa2	TCDD	Male	20Weeks	liver	-0.644640070757582	Down-regulated
26	Ptch1	TCDD	Male	20Weeks	liver	-0.64634993410716	Down-regulated
27	Hist2h2be	TCDD	Male	20Weeks	liver	-0.647691170605051	Down-regulated
28	Dtx4	TCDD	Male	20Weeks	liver	-0.648345696035618	Down-regulated
29	Gprin3	TCDD	Male	20Weeks	liver	-0.649453889916939	Down-regulated
30	1700018L02Rik	TCDD	Male	20Weeks	liver	-0.649607257915938	Down-regulated
31	Car1	TCDD	Male	20Weeks	liver	-0.650504434935975	Down-regulated
32	Slc25a34	TCDD	Male	20Weeks	liver	-0.651286421510305	Down-regulated
33	Rprd1a	TCDD	Male	20Weeks	liver	-0.657768263220675	Down-regulated
34	Exog	TCDD	Male	20Weeks	liver	-0.659586958123088	Down-regulated
35	Zfp760	TCDD	Male	20Weeks	liver	-0.660167439502984	Down-regulated
36	Tmed3	TCDD	Male	20Weeks	liver	-0.661711431566688	Down-regulated
37	Trim65	TCDD	Male	20Weeks	liver	-0.668494511501963	Down-regulated
38	Letm2	TCDD	Male	20Weeks	liver	-0.668668875564237	Down-regulated
39	Lgalsl	TCDD	Male	20Weeks	liver	-0.67501037351832	Down-regulated
40	Hsp90ab1	TCDD	Male	20Weeks	liver	-0.677141411402974	Down-regulated
41	Tspyl2	TCDD	Male	20Weeks	liver	-0.681451898564443	Down-regulated
42	Pim1	TCDD	Male	20Weeks	liver	-0.688508794211013	Down-regulated
43	Sdf2l1	TCDD	Male	20Weeks	liver	-0.689750611637335	Down-regulated
44	Ptges3-ps	TCDD	Male	20Weeks	liver	-0.692953344172222	Down-regulated
45	Jun	TCDD	Male	20Weeks	liver	-0.697561629080149	Down-regulated
46	Cldn1	TCDD	Male	20Weeks	liver	-0.705537890239352	Down-regulated
47	Cdk2ap2	TCDD	Male	20Weeks	liver	-0.711522342846797	Down-regulated
48	Zmym6	TCDD	Male	20Weeks	liver	-0.714041288134396	Down-regulated
49	Syt11	TCDD	Male	20Weeks	liver	-0.716497378091134	Down-regulated
50	H2-K2	TCDD	Male	20Weeks	liver	-0.718093317614984	Down-regulated
51	Ddc	TCDD	Male	20Weeks	liver	-0.719853258314447	Down-regulated
52	Thap2	TCDD	Male	20Weeks	liver	-0.720148502006633	Down-regulated
53	Olfr1034	TCDD	Male	20Weeks	liver	-0.723147520097102	Down-regulated
54	Zbtb26	TCDD	Male	20Weeks	liver	-0.725610495712177	Down-regulated
55	Tuft1	TCDD	Male	20Weeks	liver	-0.725976559564805	Down-regulated
56	Cys1	TCDD	Male	20Weeks	liver	-0.73235608514591	Down-regulated
57	Lbhd1	TCDD	Male	20Weeks	liver	-0.741348649609031	Down-regulated
58	Mbd1	TCDD	Male	20Weeks	liver	-0.750392208550095	Down-regulated
59	Abtb2	TCDD	Male	20Weeks	liver	-0.755125639575797	Down-regulated
60	9430015G10Rik	TCDD	Male	20Weeks	liver	-0.755302007014011	Down-regulated
61	6430548M08Rik	TCDD	Male	20Weeks	liver	-0.755793770155855	Down-regulated
62	Exd1	TCDD	Male	20Weeks	liver	-0.756126357302148	Down-regulated
63	Slc45a3	TCDD	Male	20Weeks	liver	-0.756705216488548	Down-regulated
64	Csad	TCDD	Male	20Weeks	liver	-0.759314159083974	Down-regulated
65	Keg1	TCDD	Male	20Weeks	liver	-0.760235173368746	Down-regulated
66	A330023F24Rik	TCDD	Male	20Weeks	liver	-0.760859854869202	Down-regulated
67	2810013P06Rik	TCDD	Male	20Weeks	liver	-0.762180828549025	Down-regulated
68	Zbtb40	TCDD	Male	20Weeks	liver	-0.763933288408808	Down-regulated
69	Gm14410	TCDD	Male	20Weeks	liver	-0.765040305170834	Down-regulated
70	C130013H08Rik	TCDD	Male	20Weeks	liver	-0.776015440944962	Down-regulated
71	Cacybp	TCDD	Male	20Weeks	liver	-0.776290276946861	Down-regulated
72	Gfpt1	TCDD	Male	20Weeks	liver	-0.777571019270003	Down-regulated
73	Foxa2	TCDD	Male	20Weeks	liver	-0.783694293218647	Down-regulated
74	Gm15542	TCDD	Male	20Weeks	liver	-0.785421666646186	Down-regulated
75	Crem	TCDD	Male	20Weeks	liver	-0.785625197970289	Down-regulated
76	Nedd4l	TCDD	Male	20Weeks	liver	-0.790916343498743	Down-regulated
77	Gm37254	TCDD	Male	20Weeks	liver	-0.794868742758771	Down-regulated
78	Nfil3	TCDD	Male	20Weeks	liver	-0.799725380070447	Down-regulated
79	Eml6	TCDD	Male	20Weeks	liver	-0.802817487104359	Down-regulated
80	Atp2a2	TCDD	Male	20Weeks	liver	-0.806380346218912	Down-regulated
81	Cad	TCDD	Male	20Weeks	liver	-0.813949630463913	Down-regulated
82	Inhba	TCDD	Male	20Weeks	liver	-0.82686252364584	Down-regulated
83	AC161607.1	TCDD	Male	20Weeks	liver	-0.827153648242065	Down-regulated
84	Ypel2	TCDD	Male	20Weeks	liver	-0.832047701439425	Down-regulated
85	Gm7160	TCDD	Male	20Weeks	liver	-0.832675730160141	Down-regulated
86	Foxa1	TCDD	Male	20Weeks	liver	-0.837164017735994	Down-regulated
87	St5	TCDD	Male	20Weeks	liver	-0.839788005013066	Down-regulated
88	Prss53	TCDD	Male	20Weeks	liver	-0.840831673441508	Down-regulated
89	Gsta2	TCDD	Male	20Weeks	liver	-0.863331364116702	Down-regulated
90	Asap2	TCDD	Male	20Weeks	liver	-0.867416017706664	Down-regulated
91	Car3	TCDD	Male	20Weeks	liver	-0.874663954319861	Down-regulated
92	Mpp4	TCDD	Male	20Weeks	liver	-0.878489010221508	Down-regulated
93	AW011738	TCDD	Male	20Weeks	liver	-0.887472611735689	Down-regulated
94	Cyp3a11	TCDD	Male	20Weeks	liver	-0.892467094710347	Down-regulated
95	Mycl	TCDD	Male	20Weeks	liver	-0.898284211988769	Down-regulated
96	Gm16348	TCDD	Male	20Weeks	liver	-0.898518551406528	Down-regulated
97	Slc39a10	TCDD	Male	20Weeks	liver	-0.899048223513082	Down-regulated
98	Leng9	TCDD	Male	20Weeks	liver	-0.900584312188959	Down-regulated
99	P4ha1	TCDD	Male	20Weeks	liver	-0.901250706993486	Down-regulated
100	Cyp21a2-ps	TCDD	Male	20Weeks	liver	-0.90324353207834	Down-regulated
101	Serpinh1	TCDD	Male	20Weeks	liver	-0.907033991333617	Down-regulated
102	Rbm12b2	TCDD	Male	20Weeks	liver	-0.90907050062673	Down-regulated
103	Hist1h1d	TCDD	Male	20Weeks	liver	-0.940128945153095	Down-regulated
104	Slc17a8	TCDD	Male	20Weeks	liver	-0.942811077754647	Down-regulated
105	Etfbkmt	TCDD	Male	20Weeks	liver	-0.945345232138428	Down-regulated
106	Gm26967	TCDD	Male	20Weeks	liver	-0.948772917219687	Down-regulated
107	Serpina1e	TCDD	Male	20Weeks	liver	-0.968867691173622	Down-regulated
108	Tra2a	TCDD	Male	20Weeks	liver	-0.974068834050072	Down-regulated
109	Tmem266	TCDD	Male	20Weeks	liver	-0.975073873617459	Down-regulated
110	Acmsd	TCDD	Male	20Weeks	liver	-0.985894141835665	Down-regulated
111	Hspa4l	TCDD	Male	20Weeks	liver	-0.98633514148436	Down-regulated
112	Ttyh1	TCDD	Male	20Weeks	liver	-0.987652007053876	Down-regulated
113	Clpx	TCDD	Male	20Weeks	liver	-0.987732050877359	Down-regulated
114	Hist1h2be	TCDD	Male	20Weeks	liver	-0.99148859771019	Down-regulated
115	Gm16551	TCDD	Male	20Weeks	liver	-0.997414679421158	Down-regulated
116	Tes	TCDD	Male	20Weeks	liver	-0.999150683409523	Down-regulated
117	Gm35339	TCDD	Male	20Weeks	liver	-1.00347523689368	Down-regulated
118	9030616G12Rik	TCDD	Male	20Weeks	liver	-1.00514588713544	Down-regulated
119	Manf	TCDD	Male	20Weeks	liver	-1.02332861604656	Down-regulated
120	Fst	TCDD	Male	20Weeks	liver	-1.05480004751248	Down-regulated
121	Dnaja4	TCDD	Male	20Weeks	liver	-1.07113038521375	Down-regulated
122	Hspa1a	TCDD	Male	20Weeks	liver	-1.10238021805615	Down-regulated
123	Gm15459	TCDD	Male	20Weeks	liver	-1.10780355966556	Down-regulated
124	Chordc1	TCDD	Male	20Weeks	liver	-1.11800320567706	Down-regulated
125	Hspa5	TCDD	Male	20Weeks	liver	-1.14336678413406	Down-regulated
126	Stip1	TCDD	Male	20Weeks	liver	-1.14420144823409	Down-regulated
127	Dusp8	TCDD	Male	20Weeks	liver	-1.14421482561444	Down-regulated
128	Rbm12b1	TCDD	Male	20Weeks	liver	-1.16130772542628	Down-regulated
129	BC021767	TCDD	Male	20Weeks	liver	-1.17969857327012	Down-regulated
130	Hspa8	TCDD	Male	20Weeks	liver	-1.18243646241982	Down-regulated
131	Gm35696	TCDD	Male	20Weeks	liver	-1.18299472043675	Down-regulated
132	Hist2h4	TCDD	Male	20Weeks	liver	-1.19666566712783	Down-regulated
133	Cdc42ep5	TCDD	Male	20Weeks	liver	-1.19986234596898	Down-regulated
134	Hsp90aa1	TCDD	Male	20Weeks	liver	-1.2138310354907	Down-regulated
135	Mthfr	TCDD	Male	20Weeks	liver	-1.24400392272453	Down-regulated
136	Hyou1	TCDD	Male	20Weeks	liver	-1.2490715651816	Down-regulated
137	E2f8	TCDD	Male	20Weeks	liver	-1.31512502740242	Down-regulated
138	9430037G07Rik	TCDD	Male	20Weeks	liver	-1.33391558242738	Down-regulated
139	Slc5a3	TCDD	Male	20Weeks	liver	-1.33562686228688	Down-regulated
140	Apoe	TCDD	Male	20Weeks	liver	-1.35485692455159	Down-regulated
141	Adgrf1	TCDD	Male	20Weeks	liver	-1.35962536330047	Down-regulated
142	Onecut1	TCDD	Male	20Weeks	liver	-1.36494189521799	Down-regulated
143	Chka	TCDD	Male	20Weeks	liver	-1.37247979919019	Down-regulated
144	Fgf21	TCDD	Male	20Weeks	liver	-1.39903792727817	Down-regulated
145	Fam198a	TCDD	Male	20Weeks	liver	-1.40782627473588	Down-regulated
146	Hspb1	TCDD	Male	20Weeks	liver	-1.46730287630946	Down-regulated
147	Serpina4-ps1	TCDD	Male	20Weeks	liver	-1.4683486725504	Down-regulated
148	Zbtb16	TCDD	Male	20Weeks	liver	-1.48890972791928	Down-regulated
149	Btg2	TCDD	Male	20Weeks	liver	-1.53195444450235	Down-regulated
150	Syvn1	TCDD	Male	20Weeks	liver	-1.54552042927116	Down-regulated
151	Ugt2b38	TCDD	Male	20Weeks	liver	-1.54632578428849	Down-regulated
152	Gm38070	TCDD	Male	20Weeks	liver	-1.57611635819098	Down-regulated
153	Elovl3	TCDD	Male	20Weeks	liver	-1.58386977134845	Down-regulated
154	Socs2	TCDD	Male	20Weeks	liver	-1.59111935804253	Down-regulated
155	Gtpbp4-ps1	TCDD	Male	20Weeks	liver	-1.67473372254542	Down-regulated
156	3930402G23Rik	TCDD	Male	20Weeks	liver	-1.70804931150267	Down-regulated
157	Cib3	TCDD	Male	20Weeks	liver	-1.7361361736562	Down-regulated
158	Slc25a30	TCDD	Male	20Weeks	liver	-1.78815316839982	Down-regulated
159	Dhrs9	TCDD	Male	20Weeks	liver	-1.80765798538226	Down-regulated
160	Arntl	TCDD	Male	20Weeks	liver	-1.83078558918573	Down-regulated
161	Peg10	TCDD	Male	20Weeks	liver	-1.83863581538049	Down-regulated
162	Creld2	TCDD	Male	20Weeks	liver	-1.83897118086963	Down-regulated
163	Hsph1	TCDD	Male	20Weeks	liver	-1.87294303580922	Down-regulated
164	Cyp26b1	TCDD	Male	20Weeks	liver	-2.02897678987252	Down-regulated
165	Tff3	TCDD	Male	20Weeks	liver	-2.04866888891299	Down-regulated
166	Hspa1b	TCDD	Male	20Weeks	liver	-2.05852808188165	Down-regulated
167	Egr1	TCDD	Male	20Weeks	liver	-2.06500150365941	Down-regulated
168	Selenbp2	TCDD	Male	20Weeks	liver	-2.07585912400685	Down-regulated
169	Npas2	TCDD	Male	20Weeks	liver	-2.77468639733658	Down-regulated