ToxiTaRGET Database of Toxicant Exposures and Response
As BPA10mg BPA10ug DEHP Pb PM2.5(JHK) PM2.5(CHI) TBT TCDD


Introduction: Tributyltin (TBT) is an organotin compound used in various industrial applications, primarily as an antifouling agent in marine paints. It has faced increasing scrutiny due to its adverse environmental effects and potential health risks. TBT compounds, including tributyltin oxide (TBTO), are known for their toxic properties and have been a subject of concern for their environmental impact and harmful effects on aquatic ecosystems.

Additional Resources
Environmental Protection Agency: Fact Sheet

Table1. Number of differentially expressed gene under TBT exposure.
AgeTissuesSexUp-regulatedDown-regulated
3 WeeksBlood00
00
Liver2844
1919
20 WeeksBlood635690
6171209
Liver210215
230237
40 WeeksLiver109
1019
Table2. Number of differentially accessible regions under TBT exposure.
AgeTissuesSexDAR
3 WeeksLiver392
831
20 WeeksBlood2943
910
Liver2244
3341
Table3. Number of differentially methylated regions under TBT exposure.
AgeTissuesSexHypomethylatedHypermethylated
20 WeeksBlood1837542
432258
Liver1701615859
14734737