ToxiTaRGET

As BPA10mg BPA10ug DEHP Pb PM2.5(JHK) PM2.5(CHI) TBT TCDD

Table1. Number of differentially up-regulated gene in 20 weeks female liver under Pb exposure.

No.	Gene	Exposure	Sex	Age	Tissue	Fold-change	DEG
1	Ly6d	Pb	Female	20Weeks	liver	1.56181926311466	Up-regulated
2	BC023105	Pb	Female	20Weeks	liver	1.50191778829304	Up-regulated
3	4933411K16Rik	Pb	Female	20Weeks	liver	1.34184159807445	Up-regulated
4	Adcy5	Pb	Female	20Weeks	liver	1.26368134412059	Up-regulated
5	Gm5096	Pb	Female	20Weeks	liver	1.25586860840838	Up-regulated
6	Tgtp1	Pb	Female	20Weeks	liver	1.25386843335481	Up-regulated
7	Lad1	Pb	Female	20Weeks	liver	1.18866178100679	Up-regulated
8	Ston1	Pb	Female	20Weeks	liver	1.17430412200837	Up-regulated
9	4732463B04Rik	Pb	Female	20Weeks	liver	1.15349689020558	Up-regulated
10	Zbtb45	Pb	Female	20Weeks	liver	1.11825800284699	Up-regulated
11	Ephb6	Pb	Female	20Weeks	liver	1.09131127758544	Up-regulated
12	Mtmr11	Pb	Female	20Weeks	liver	1.0842874792869	Up-regulated
13	Gpr153	Pb	Female	20Weeks	liver	1.08389800931116	Up-regulated
14	Hist1h4b	Pb	Female	20Weeks	liver	1.08340160227598	Up-regulated
15	Btbd8	Pb	Female	20Weeks	liver	1.07171569343869	Up-regulated
16	Gm10095	Pb	Female	20Weeks	liver	1.07136783269838	Up-regulated
17	Col1a1	Pb	Female	20Weeks	liver	1.05480818448546	Up-regulated
18	Hba-a1	Pb	Female	20Weeks	liver	1.04852766274415	Up-regulated
19	Mvd	Pb	Female	20Weeks	liver	1.04436159066172	Up-regulated
20	Sytl5	Pb	Female	20Weeks	liver	1.03992528953301	Up-regulated
21	Zfp41	Pb	Female	20Weeks	liver	1.01700044755867	Up-regulated
22	Uprt	Pb	Female	20Weeks	liver	1.00580278169583	Up-regulated
23	Acta2	Pb	Female	20Weeks	liver	0.997051873229253	Up-regulated
24	Hist1h1e	Pb	Female	20Weeks	liver	0.992787884666547	Up-regulated
25	Tom1	Pb	Female	20Weeks	liver	0.977175562939398	Up-regulated
26	Pkp3	Pb	Female	20Weeks	liver	0.976288613074882	Up-regulated
27	Ms4a8a	Pb	Female	20Weeks	liver	0.975328069682206	Up-regulated
28	Cyp1b1	Pb	Female	20Weeks	liver	0.973004087206924	Up-regulated
29	Myh11	Pb	Female	20Weeks	liver	0.96531399268031	Up-regulated
30	Hspb1	Pb	Female	20Weeks	liver	0.961024322348027	Up-regulated
31	mt-Co3	Pb	Female	20Weeks	liver	0.956018241769632	Up-regulated
32	Ltbp2	Pb	Female	20Weeks	liver	0.94801777703427	Up-regulated
33	Cbfa2t3	Pb	Female	20Weeks	liver	0.945949783400743	Up-regulated
34	Rpusd1	Pb	Female	20Weeks	liver	0.943479415265238	Up-regulated
35	Gm7463	Pb	Female	20Weeks	liver	0.939241849777147	Up-regulated
36	Slfn8	Pb	Female	20Weeks	liver	0.937865136513412	Up-regulated
37	Rnf150	Pb	Female	20Weeks	liver	0.937154746055379	Up-regulated
38	Nr1d1	Pb	Female	20Weeks	liver	0.935932901012021	Up-regulated
39	Snx29	Pb	Female	20Weeks	liver	0.927938193365408	Up-regulated
40	Col6a2	Pb	Female	20Weeks	liver	0.925966690521602	Up-regulated
41	Fam120c	Pb	Female	20Weeks	liver	0.922560398762241	Up-regulated
42	Catsperd	Pb	Female	20Weeks	liver	0.917709535690507	Up-regulated
43	Gm8566	Pb	Female	20Weeks	liver	0.916332225116293	Up-regulated
44	Gm1821	Pb	Female	20Weeks	liver	0.911090720417968	Up-regulated
45	mt-Co2	Pb	Female	20Weeks	liver	0.90645130493711	Up-regulated
46	Gm6206	Pb	Female	20Weeks	liver	0.899774971247802	Up-regulated
47	Ksr1	Pb	Female	20Weeks	liver	0.897117729298932	Up-regulated
48	Hist1h4d	Pb	Female	20Weeks	liver	0.888353782974374	Up-regulated
49	4933431E20Rik	Pb	Female	20Weeks	liver	0.882985644425476	Up-regulated
50	Gm13657	Pb	Female	20Weeks	liver	0.881677733031386	Up-regulated
51	Gale	Pb	Female	20Weeks	liver	0.876467694165677	Up-regulated
52	Gm45640	Pb	Female	20Weeks	liver	0.875515472728623	Up-regulated
53	Atp2b2	Pb	Female	20Weeks	liver	0.862256905989637	Up-regulated
54	A930004J17Rik	Pb	Female	20Weeks	liver	0.861256300106459	Up-regulated
55	Stx1b	Pb	Female	20Weeks	liver	0.857903249542665	Up-regulated
56	Exph5	Pb	Female	20Weeks	liver	0.857685319819294	Up-regulated
57	Ankrd13b	Pb	Female	20Weeks	liver	0.857386729325847	Up-regulated
58	Sema5a	Pb	Female	20Weeks	liver	0.856848110757202	Up-regulated
59	Prr12	Pb	Female	20Weeks	liver	0.85654477175161	Up-regulated
60	Zfp628	Pb	Female	20Weeks	liver	0.850800492750961	Up-regulated
61	Krt19	Pb	Female	20Weeks	liver	0.843469764356515	Up-regulated
62	Trim62	Pb	Female	20Weeks	liver	0.842456669971676	Up-regulated
63	Pcyox1l	Pb	Female	20Weeks	liver	0.840476541027191	Up-regulated
64	Lrp5	Pb	Female	20Weeks	liver	0.840365088450407	Up-regulated
65	H2-Eb1	Pb	Female	20Weeks	liver	0.838289176632049	Up-regulated
66	Eln	Pb	Female	20Weeks	liver	0.834908209610203	Up-regulated
67	Spef1	Pb	Female	20Weeks	liver	0.821714316607488	Up-regulated
68	Astn2	Pb	Female	20Weeks	liver	0.820706572838489	Up-regulated
69	Gstp-ps	Pb	Female	20Weeks	liver	0.814977837076997	Up-regulated
70	Phactr1	Pb	Female	20Weeks	liver	0.81316376163152	Up-regulated
71	Mapkapk3	Pb	Female	20Weeks	liver	0.812039310901911	Up-regulated
72	Got2-ps1	Pb	Female	20Weeks	liver	0.810980050963625	Up-regulated
73	Zbed3	Pb	Female	20Weeks	liver	0.81094886103471	Up-regulated
74	Dlg4	Pb	Female	20Weeks	liver	0.810909039962403	Up-regulated
75	P2ry4	Pb	Female	20Weeks	liver	0.810578135622293	Up-regulated
76	Dtx4	Pb	Female	20Weeks	liver	0.809302248391626	Up-regulated
77	Pltp	Pb	Female	20Weeks	liver	0.80388442658801	Up-regulated
78	Sf3a2	Pb	Female	20Weeks	liver	0.803189526359631	Up-regulated
79	Lama1	Pb	Female	20Weeks	liver	0.800552285529767	Up-regulated
80	Gsdme	Pb	Female	20Weeks	liver	0.799950198142037	Up-regulated
81	Mob3a	Pb	Female	20Weeks	liver	0.796854597478977	Up-regulated
82	Trim80	Pb	Female	20Weeks	liver	0.796061509650579	Up-regulated
83	Tmed10-ps	Pb	Female	20Weeks	liver	0.795576193377967	Up-regulated
84	Nkd1	Pb	Female	20Weeks	liver	0.793851010514452	Up-regulated
85	Gm10250	Pb	Female	20Weeks	liver	0.791369496062595	Up-regulated
86	H2-Aa	Pb	Female	20Weeks	liver	0.790183034642348	Up-regulated
87	Mms22l	Pb	Female	20Weeks	liver	0.788739880003852	Up-regulated
88	Eps8l2	Pb	Female	20Weeks	liver	0.786856783160022	Up-regulated
89	H2-Ab1	Pb	Female	20Weeks	liver	0.78667495199674	Up-regulated
90	Mrnip	Pb	Female	20Weeks	liver	0.785340755025349	Up-regulated
91	Rab11fip5	Pb	Female	20Weeks	liver	0.783426325868292	Up-regulated
92	Papss1	Pb	Female	20Weeks	liver	0.782207162661909	Up-regulated
93	Reep4	Pb	Female	20Weeks	liver	0.780558492254578	Up-regulated
94	Gm11808	Pb	Female	20Weeks	liver	0.779816263103779	Up-regulated
95	Zscan20	Pb	Female	20Weeks	liver	0.777511272085977	Up-regulated
96	Htra3	Pb	Female	20Weeks	liver	0.77570570934157	Up-regulated
97	Atf5	Pb	Female	20Weeks	liver	0.773801088152031	Up-regulated
98	Ubald1	Pb	Female	20Weeks	liver	0.772568803902745	Up-regulated
99	Sybu	Pb	Female	20Weeks	liver	0.765283458870512	Up-regulated
100	Arid3a	Pb	Female	20Weeks	liver	0.762403308531316	Up-regulated
101	Ppp1r3e	Pb	Female	20Weeks	liver	0.761810630691264	Up-regulated
102	Lacc1	Pb	Female	20Weeks	liver	0.759593783060562	Up-regulated
103	Kctd13	Pb	Female	20Weeks	liver	0.752410787576517	Up-regulated
104	Gm11586	Pb	Female	20Weeks	liver	0.751959143514134	Up-regulated
105	Prdm11	Pb	Female	20Weeks	liver	0.751081815533063	Up-regulated
106	Katnb1	Pb	Female	20Weeks	liver	0.748392437040855	Up-regulated
107	Neurl2	Pb	Female	20Weeks	liver	0.746248894163865	Up-regulated
108	Rab11fip4	Pb	Female	20Weeks	liver	0.741493241948331	Up-regulated
109	Bub1b	Pb	Female	20Weeks	liver	0.740331503442518	Up-regulated
110	Tjp3	Pb	Female	20Weeks	liver	0.736692515216231	Up-regulated
111	Ifi27l2b	Pb	Female	20Weeks	liver	0.736491121923702	Up-regulated
112	D630045J12Rik	Pb	Female	20Weeks	liver	0.736129747846661	Up-regulated
113	Gpam	Pb	Female	20Weeks	liver	0.734168563832671	Up-regulated
114	Hk3	Pb	Female	20Weeks	liver	0.734144360094694	Up-regulated
115	Drc1	Pb	Female	20Weeks	liver	0.728294803035722	Up-regulated
116	Bicdl1	Pb	Female	20Weeks	liver	0.725274914083452	Up-regulated
117	Syne3	Pb	Female	20Weeks	liver	0.724656754332295	Up-regulated
118	Cd274	Pb	Female	20Weeks	liver	0.723343337248512	Up-regulated
119	Acnat2	Pb	Female	20Weeks	liver	0.723011521391083	Up-regulated
120	Ddr1	Pb	Female	20Weeks	liver	0.722611488436459	Up-regulated
121	Gm3699	Pb	Female	20Weeks	liver	0.7216945139052	Up-regulated
122	Peak1	Pb	Female	20Weeks	liver	0.720549738251094	Up-regulated
123	Zscan22	Pb	Female	20Weeks	liver	0.720254832797623	Up-regulated
124	Lzts2	Pb	Female	20Weeks	liver	0.720247338653691	Up-regulated
125	Cd74	Pb	Female	20Weeks	liver	0.720167100342223	Up-regulated
126	Dhx34	Pb	Female	20Weeks	liver	0.71343565201237	Up-regulated
127	Gfod1	Pb	Female	20Weeks	liver	0.713051763929286	Up-regulated
128	Fbxl8	Pb	Female	20Weeks	liver	0.709566171926277	Up-regulated
129	Serinc2	Pb	Female	20Weeks	liver	0.704620986444511	Up-regulated
130	1010001N08Rik	Pb	Female	20Weeks	liver	0.70251043188598	Up-regulated
131	Dll1	Pb	Female	20Weeks	liver	0.696827897745258	Up-regulated
132	Fam129b	Pb	Female	20Weeks	liver	0.696683300881122	Up-regulated
133	Them6	Pb	Female	20Weeks	liver	0.695410494204853	Up-regulated
134	Fam198a	Pb	Female	20Weeks	liver	0.695237957895638	Up-regulated
135	Smo	Pb	Female	20Weeks	liver	0.694767043956509	Up-regulated
136	Mbnl3	Pb	Female	20Weeks	liver	0.693533437908148	Up-regulated
137	Jrk	Pb	Female	20Weeks	liver	0.693330351736851	Up-regulated
138	Gmip	Pb	Female	20Weeks	liver	0.691717338109141	Up-regulated
139	Gm13021	Pb	Female	20Weeks	liver	0.691567025873194	Up-regulated
140	Gm13341	Pb	Female	20Weeks	liver	0.691493606134632	Up-regulated
141	Gm15427	Pb	Female	20Weeks	liver	0.691251971603553	Up-regulated
142	Ppargc1b	Pb	Female	20Weeks	liver	0.690815359400071	Up-regulated
143	Acvr1b	Pb	Female	20Weeks	liver	0.685337925335858	Up-regulated
144	Proser3	Pb	Female	20Weeks	liver	0.683645539019889	Up-regulated
145	Fancm	Pb	Female	20Weeks	liver	0.683501087770493	Up-regulated
146	Nav2	Pb	Female	20Weeks	liver	0.683330494348833	Up-regulated
147	Crybg2	Pb	Female	20Weeks	liver	0.682226101470135	Up-regulated
148	Zfp414	Pb	Female	20Weeks	liver	0.679425235787926	Up-regulated
149	Aqp8	Pb	Female	20Weeks	liver	0.67700966297376	Up-regulated
150	Bbc3	Pb	Female	20Weeks	liver	0.676251783762644	Up-regulated
151	Mmab	Pb	Female	20Weeks	liver	0.675891645394953	Up-regulated
152	Thtpa	Pb	Female	20Weeks	liver	0.675627904231026	Up-regulated
153	Hist1h2be	Pb	Female	20Weeks	liver	0.675336357776613	Up-regulated
154	Adm	Pb	Female	20Weeks	liver	0.674885826615599	Up-regulated
155	Zfp691	Pb	Female	20Weeks	liver	0.672477973105664	Up-regulated
156	Col6a1	Pb	Female	20Weeks	liver	0.671635688767786	Up-regulated
157	Alg8	Pb	Female	20Weeks	liver	0.670378251544829	Up-regulated
158	Ank2	Pb	Female	20Weeks	liver	0.669326739117469	Up-regulated
159	Gm13889	Pb	Female	20Weeks	liver	0.668127656221843	Up-regulated
160	Hmga1	Pb	Female	20Weeks	liver	0.666365413178058	Up-regulated
161	Fam122a	Pb	Female	20Weeks	liver	0.663671407784169	Up-regulated
162	Col5a1	Pb	Female	20Weeks	liver	0.663080466168823	Up-regulated
163	Tdp1	Pb	Female	20Weeks	liver	0.66273164534977	Up-regulated
164	Grwd1	Pb	Female	20Weeks	liver	0.662126968479035	Up-regulated
165	Gm17753	Pb	Female	20Weeks	liver	0.661292457743733	Up-regulated
166	Nfkb2	Pb	Female	20Weeks	liver	0.661047930979494	Up-regulated
167	Adamts13	Pb	Female	20Weeks	liver	0.659511547733405	Up-regulated
168	Rccd1	Pb	Female	20Weeks	liver	0.658649900124385	Up-regulated
169	Inafm1	Pb	Female	20Weeks	liver	0.656740014304373	Up-regulated
170	Zfp90	Pb	Female	20Weeks	liver	0.656569659076456	Up-regulated
171	Jund	Pb	Female	20Weeks	liver	0.65455222220079	Up-regulated
172	Lrfn3	Pb	Female	20Weeks	liver	0.652890239450933	Up-regulated
173	Slc10a5	Pb	Female	20Weeks	liver	0.652684642546368	Up-regulated
174	Rab11fip1	Pb	Female	20Weeks	liver	0.652655715286239	Up-regulated
175	Hmgcs1	Pb	Female	20Weeks	liver	0.652014032130554	Up-regulated
176	Zfp3	Pb	Female	20Weeks	liver	0.649307486059394	Up-regulated
177	Gm42604	Pb	Female	20Weeks	liver	0.648725683035459	Up-regulated
178	Cytip	Pb	Female	20Weeks	liver	0.647837999463945	Up-regulated
179	Pde9a	Pb	Female	20Weeks	liver	0.64527459735042	Up-regulated
180	5830417I10Rik	Pb	Female	20Weeks	liver	0.644735108786524	Up-regulated
181	Kcnk6	Pb	Female	20Weeks	liver	0.644509614068079	Up-regulated
182	Sirt6	Pb	Female	20Weeks	liver	0.642823723743938	Up-regulated
183	Zfhx4	Pb	Female	20Weeks	liver	0.642478297279241	Up-regulated
184	Arv1	Pb	Female	20Weeks	liver	0.64232727988336	Up-regulated
185	Kmt2d	Pb	Female	20Weeks	liver	0.642043381117754	Up-regulated
186	Plekhg2	Pb	Female	20Weeks	liver	0.641337622370439	Up-regulated
187	Fam83g	Pb	Female	20Weeks	liver	0.639802381407583	Up-regulated
188	S100a10	Pb	Female	20Weeks	liver	0.637297493261523	Up-regulated
189	Hspbap1	Pb	Female	20Weeks	liver	0.637285196212349	Up-regulated
190	Ptpn14	Pb	Female	20Weeks	liver	0.632746901400844	Up-regulated
191	Slc39a5	Pb	Female	20Weeks	liver	0.632393727522747	Up-regulated
192	Gm28661	Pb	Female	20Weeks	liver	0.631357542263462	Up-regulated
193	Bcam	Pb	Female	20Weeks	liver	0.630985393792152	Up-regulated
194	Capn5	Pb	Female	20Weeks	liver	0.62882022386358	Up-regulated
195	Kdf1	Pb	Female	20Weeks	liver	0.628257974670676	Up-regulated
196	Gpx4-ps2	Pb	Female	20Weeks	liver	0.62788198662838	Up-regulated
197	Gm12481	Pb	Female	20Weeks	liver	0.62568960397937	Up-regulated
198	Ripk2	Pb	Female	20Weeks	liver	0.62415540453118	Up-regulated
199	Galns	Pb	Female	20Weeks	liver	0.622977081380365	Up-regulated
200	Dzip3	Pb	Female	20Weeks	liver	0.622783011350178	Up-regulated
201	Shank2	Pb	Female	20Weeks	liver	0.622366867238004	Up-regulated
202	Fbxl21	Pb	Female	20Weeks	liver	0.622000215988771	Up-regulated
203	Plekha1	Pb	Female	20Weeks	liver	0.619816674408666	Up-regulated
204	Syne1	Pb	Female	20Weeks	liver	0.618384608971616	Up-regulated
205	Zbtb12	Pb	Female	20Weeks	liver	0.618253176196181	Up-regulated
206	Tmc8	Pb	Female	20Weeks	liver	0.617822412802803	Up-regulated
207	Rnf39	Pb	Female	20Weeks	liver	0.617696515165449	Up-regulated
208	Emp1	Pb	Female	20Weeks	liver	0.61614057719141	Up-regulated
209	Gstm2	Pb	Female	20Weeks	liver	0.616000224805777	Up-regulated
210	Mical2	Pb	Female	20Weeks	liver	0.613953010765439	Up-regulated
211	Abcb9	Pb	Female	20Weeks	liver	0.613879280543143	Up-regulated
212	Gm49494	Pb	Female	20Weeks	liver	0.61253937935548	Up-regulated
213	Plec	Pb	Female	20Weeks	liver	0.611616930495783	Up-regulated
214	Tln2	Pb	Female	20Weeks	liver	0.610808251335904	Up-regulated
215	Daam2	Pb	Female	20Weeks	liver	0.609831831171542	Up-regulated
216	Ppp1r9b	Pb	Female	20Weeks	liver	0.609094355364478	Up-regulated
217	Mapk15	Pb	Female	20Weeks	liver	0.609090423702107	Up-regulated
218	Ift122	Pb	Female	20Weeks	liver	0.607651797867862	Up-regulated
219	Card10	Pb	Female	20Weeks	liver	0.607502685695487	Up-regulated
220	Med18	Pb	Female	20Weeks	liver	0.60697185045251	Up-regulated
221	Klhl18	Pb	Female	20Weeks	liver	0.606951049034643	Up-regulated
222	Psd4	Pb	Female	20Weeks	liver	0.603861361700543	Up-regulated
223	Pcsk5	Pb	Female	20Weeks	liver	0.603523827538515	Up-regulated
224	Gm11437	Pb	Female	20Weeks	liver	0.603298630385586	Up-regulated
225	Lrrc32	Pb	Female	20Weeks	liver	0.602499071329686	Up-regulated
226	Trappc9	Pb	Female	20Weeks	liver	0.602198290547983	Up-regulated
227	Cd59b	Pb	Female	20Weeks	liver	0.600736471625577	Up-regulated
228	Zfp385a	Pb	Female	20Weeks	liver	0.600330943741176	Up-regulated
229	Mink1	Pb	Female	20Weeks	liver	0.598175610263869	Up-regulated
230	Kank2	Pb	Female	20Weeks	liver	0.598120654542539	Up-regulated
231	Glis2	Pb	Female	20Weeks	liver	0.597547488386539	Up-regulated
232	Med24	Pb	Female	20Weeks	liver	0.596901900463416	Up-regulated
233	4930480K23Rik	Pb	Female	20Weeks	liver	0.59677297223859	Up-regulated
234	Pde1a	Pb	Female	20Weeks	liver	0.596412886501795	Up-regulated
235	Lmtk2	Pb	Female	20Weeks	liver	0.594424026165786	Up-regulated
236	Gm4149	Pb	Female	20Weeks	liver	0.593895037688797	Up-regulated
237	Ttc28	Pb	Female	20Weeks	liver	0.593010427748033	Up-regulated
238	Arhgap10	Pb	Female	20Weeks	liver	0.593002223216168	Up-regulated
239	Gabra3	Pb	Female	20Weeks	liver	0.592657292785073	Up-regulated
240	Cyb561a3	Pb	Female	20Weeks	liver	0.592641203926289	Up-regulated
241	Anxa11	Pb	Female	20Weeks	liver	0.591961901142917	Up-regulated
242	Gnpda1	Pb	Female	20Weeks	liver	0.590305065397695	Up-regulated
243	Gm12166	Pb	Female	20Weeks	liver	0.589634505868681	Up-regulated
244	Nhej1	Pb	Female	20Weeks	liver	0.589284618955093	Up-regulated
245	Cul7	Pb	Female	20Weeks	liver	0.58829168033729	Up-regulated
246	4833422C13Rik	Pb	Female	20Weeks	liver	0.587765748224289	Up-regulated
247	Tgfb1i1	Pb	Female	20Weeks	liver	0.587599521155856	Up-regulated
248	Tcf21	Pb	Female	20Weeks	liver	0.585466322647245	Up-regulated
249	Trp53bp1	Pb	Female	20Weeks	liver	0.585226262104018	Up-regulated
250	Kdm2b	Pb	Female	20Weeks	liver	0.585007827315055	Up-regulated