ToxiTaRGET Database of Toxicant Exposures and Response
As BPA10mg BPA10ug DEHP Pb PM2.5(JHK) PM2.5(CHI) TBT TCDD


Table1. Number of differentially down-regulated gene in 20 weeks female liver under TBT exposure.
No.GeneExposureSexAgeTissueFold-changeDEG
1Hsph1TBTFemale20Weeksliver-0.585280736985775Down-regulated
2Gm29216TBTFemale20Weeksliver-0.586254852453285Down-regulated
3ShbTBTFemale20Weeksliver-0.586535614539037Down-regulated
4Klf13TBTFemale20Weeksliver-0.587159171384948Down-regulated
5Pcgf6TBTFemale20Weeksliver-0.589344311631351Down-regulated
6Cyp39a1TBTFemale20Weeksliver-0.590721834299068Down-regulated
7Oaz1-psTBTFemale20Weeksliver-0.591228216850035Down-regulated
8Tbc1d8TBTFemale20Weeksliver-0.592647400671758Down-regulated
9Angptl4TBTFemale20Weeksliver-0.592837340284486Down-regulated
10MaptTBTFemale20Weeksliver-0.593286228643569Down-regulated
11Nxt1TBTFemale20Weeksliver-0.594330511944388Down-regulated
12Zfp58TBTFemale20Weeksliver-0.596936499282946Down-regulated
13C1s2TBTFemale20Weeksliver-0.601945735406812Down-regulated
14Ftl1-ps1TBTFemale20Weeksliver-0.602428279556384Down-regulated
15Rps10-ps1TBTFemale20Weeksliver-0.605942619911548Down-regulated
16Ces3aTBTFemale20Weeksliver-0.608080812895733Down-regulated
17Gm15459TBTFemale20Weeksliver-0.609366617944598Down-regulated
18Gm10221TBTFemale20Weeksliver-0.611158258268646Down-regulated
19AdaTBTFemale20Weeksliver-0.615585678816487Down-regulated
20Gm10275TBTFemale20Weeksliver-0.620311923198926Down-regulated
21Ntn3TBTFemale20Weeksliver-0.622384932134474Down-regulated
224933431K14RikTBTFemale20Weeksliver-0.62325844072138Down-regulated
23Slc35g1TBTFemale20Weeksliver-0.624982892331612Down-regulated
24S1pr3TBTFemale20Weeksliver-0.625112817041954Down-regulated
25PorcnTBTFemale20Weeksliver-0.62658501401135Down-regulated
26Gm13835TBTFemale20Weeksliver-0.627509571557423Down-regulated
27Tle6TBTFemale20Weeksliver-0.630863879590172Down-regulated
28Mfsd13aTBTFemale20Weeksliver-0.630879752686454Down-regulated
29AC154378.1TBTFemale20Weeksliver-0.634054144923703Down-regulated
30Gm9794TBTFemale20Weeksliver-0.635970093603459Down-regulated
31Nup35TBTFemale20Weeksliver-0.637631879378869Down-regulated
32Rpl31-ps8TBTFemale20Weeksliver-0.63884275829173Down-regulated
33Acnat2TBTFemale20Weeksliver-0.639704914847679Down-regulated
34Pidd1TBTFemale20Weeksliver-0.641581610245979Down-regulated
35Klhl25TBTFemale20Weeksliver-0.643155414870198Down-regulated
36Angptl6TBTFemale20Weeksliver-0.643532310141258Down-regulated
37Gm10123TBTFemale20Weeksliver-0.643550375715243Down-regulated
38Rnf144aTBTFemale20Weeksliver-0.644466448197061Down-regulated
39Dusp6TBTFemale20Weeksliver-0.644806441455925Down-regulated
40DohhTBTFemale20Weeksliver-0.645249170990999Down-regulated
41Phpt1TBTFemale20Weeksliver-0.647181421402683Down-regulated
42HdcTBTFemale20Weeksliver-0.647824083263261Down-regulated
43HopxTBTFemale20Weeksliver-0.648635349332872Down-regulated
44Ccdc22TBTFemale20Weeksliver-0.649469468174482Down-regulated
45Smim6TBTFemale20Weeksliver-0.664491719054739Down-regulated
46Gm7536TBTFemale20Weeksliver-0.669737508897003Down-regulated
47Gtf2ird2TBTFemale20Weeksliver-0.671513575911839Down-regulated
48Insig2TBTFemale20Weeksliver-0.673042409031503Down-regulated
49Slc39a5TBTFemale20Weeksliver-0.677042133969154Down-regulated
50St3gal5TBTFemale20Weeksliver-0.677369962638445Down-regulated
51Ms4a8aTBTFemale20Weeksliver-0.679937753277683Down-regulated
52Rpl3-ps1TBTFemale20Weeksliver-0.680925420265297Down-regulated
53SmagpTBTFemale20Weeksliver-0.685102291534008Down-regulated
54Frat2TBTFemale20Weeksliver-0.68612552926253Down-regulated
55Igf2bp2TBTFemale20Weeksliver-0.686476363165445Down-regulated
56Il34TBTFemale20Weeksliver-0.689375183264277Down-regulated
57D430019H16RikTBTFemale20Weeksliver-0.690522448675598Down-regulated
58Ccng2TBTFemale20Weeksliver-0.691490232257222Down-regulated
59AdprhTBTFemale20Weeksliver-0.694249019870819Down-regulated
60Gm28661TBTFemale20Weeksliver-0.694284414736888Down-regulated
61Gm3699TBTFemale20Weeksliver-0.696045974643015Down-regulated
62Lrfn3TBTFemale20Weeksliver-0.696232132663891Down-regulated
63Med18TBTFemale20Weeksliver-0.696890353335909Down-regulated
64Dnaaf2TBTFemale20Weeksliver-0.704293836371949Down-regulated
65Tedc2TBTFemale20Weeksliver-0.704491992773542Down-regulated
66Arid3aTBTFemale20Weeksliver-0.707933589016951Down-regulated
67Pck1TBTFemale20Weeksliver-0.708884015602425Down-regulated
68Me1TBTFemale20Weeksliver-0.71093399464153Down-regulated
69Zfp689TBTFemale20Weeksliver-0.711120775185611Down-regulated
70Slc25a29TBTFemale20Weeksliver-0.713076735426429Down-regulated
71Lag3TBTFemale20Weeksliver-0.716106271407813Down-regulated
72Vcp-rsTBTFemale20Weeksliver-0.720301792672682Down-regulated
73Gm9385TBTFemale20Weeksliver-0.721666208028961Down-regulated
74Cyp2d40TBTFemale20Weeksliver-0.72207509236006Down-regulated
75Ppp1r3bTBTFemale20Weeksliver-0.722900498490424Down-regulated
76MypopTBTFemale20Weeksliver-0.726342811461883Down-regulated
77Gm10605TBTFemale20Weeksliver-0.726608816099991Down-regulated
78Gm20337TBTFemale20Weeksliver-0.726997691262904Down-regulated
79Gm4149TBTFemale20Weeksliver-0.730962200653043Down-regulated
80Hirip3TBTFemale20Weeksliver-0.731211220470317Down-regulated
81NcmapTBTFemale20Weeksliver-0.733235136298504Down-regulated
82Gm44096TBTFemale20Weeksliver-0.73945649329989Down-regulated
83Rpl9-ps6TBTFemale20Weeksliver-0.742676346179238Down-regulated
84Prss53TBTFemale20Weeksliver-0.748795859059483Down-regulated
85Gm16378TBTFemale20Weeksliver-0.754827953682031Down-regulated
86Cep97TBTFemale20Weeksliver-0.755279210891941Down-regulated
87Gm4332TBTFemale20Weeksliver-0.756665083319246Down-regulated
88Gm11478TBTFemale20Weeksliver-0.758143099319165Down-regulated
89Ces3bTBTFemale20Weeksliver-0.759845628003426Down-regulated
90Shld2TBTFemale20Weeksliver-0.762680992273493Down-regulated
91Rpl24TBTFemale20Weeksliver-0.763991030889408Down-regulated
92Trp53inp2TBTFemale20Weeksliver-0.765956723977666Down-regulated
93FdpsTBTFemale20Weeksliver-0.769355114205744Down-regulated
94FibinTBTFemale20Weeksliver-0.771932684195397Down-regulated
95Gfod1TBTFemale20Weeksliver-0.774938756181225Down-regulated
96Tubd1TBTFemale20Weeksliver-0.776425501967701Down-regulated
97Gm16740TBTFemale20Weeksliver-0.778281333498366Down-regulated
98Gm28557TBTFemale20Weeksliver-0.778772882327743Down-regulated
99Nxpe2TBTFemale20Weeksliver-0.781514202965869Down-regulated
100Zbtb40TBTFemale20Weeksliver-0.78659655369581Down-regulated
101Gm7204TBTFemale20Weeksliver-0.789225242708788Down-regulated
102Slc16a11TBTFemale20Weeksliver-0.789278963823744Down-regulated
103Wnt9bTBTFemale20Weeksliver-0.789788858252565Down-regulated
104Gm42067TBTFemale20Weeksliver-0.798143767000796Down-regulated
105Slc30a10TBTFemale20Weeksliver-0.803153668395461Down-regulated
106Hspa1bTBTFemale20Weeksliver-0.8041884858147Down-regulated
1079030619P08RikTBTFemale20Weeksliver-0.809184217852904Down-regulated
108Gm15772TBTFemale20Weeksliver-0.815132311073864Down-regulated
109Itgb3TBTFemale20Weeksliver-0.819302203661862Down-regulated
110Tspyl4TBTFemale20Weeksliver-0.831917714771578Down-regulated
111G6pdxTBTFemale20Weeksliver-0.83896990730185Down-regulated
112Fam198aTBTFemale20Weeksliver-0.845847698773952Down-regulated
113Tmc7TBTFemale20Weeksliver-0.846191114471556Down-regulated
114HhipTBTFemale20Weeksliver-0.851239557283126Down-regulated
115Rps27rtTBTFemale20Weeksliver-0.852820961080784Down-regulated
116Slc25a33TBTFemale20Weeksliver-0.852991222795306Down-regulated
117Chst13TBTFemale20Weeksliver-0.857202195227883Down-regulated
118Serpina3kTBTFemale20Weeksliver-0.859830086297761Down-regulated
119Gm20528TBTFemale20Weeksliver-0.860231735796815Down-regulated
120Glt28d2TBTFemale20Weeksliver-0.860284573471879Down-regulated
121Gm49201TBTFemale20Weeksliver-0.860434510898061Down-regulated
122Errfi1TBTFemale20Weeksliver-0.863139667998745Down-regulated
123Gm5182TBTFemale20Weeksliver-0.864348716419291Down-regulated
124Ndrg1TBTFemale20Weeksliver-0.869884623894689Down-regulated
125Cyp2c50TBTFemale20Weeksliver-0.871630866983796Down-regulated
126Sult2a8TBTFemale20Weeksliver-0.876524298640018Down-regulated
127AC161607.1TBTFemale20Weeksliver-0.880382179802148Down-regulated
128Fkbp5TBTFemale20Weeksliver-0.884986219081765Down-regulated
129Rrm2TBTFemale20Weeksliver-0.886230381746189Down-regulated
130Avpr1aTBTFemale20Weeksliver-0.887452302716149Down-regulated
131Pdzk1ip1TBTFemale20Weeksliver-0.888358346552301Down-regulated
132Nfil3TBTFemale20Weeksliver-0.894187246860053Down-regulated
133Gm11273TBTFemale20Weeksliver-0.895700598108988Down-regulated
134Gm44805TBTFemale20Weeksliver-0.906857934438251Down-regulated
135Mup3TBTFemale20Weeksliver-0.912386509560443Down-regulated
136Lonrf3TBTFemale20Weeksliver-0.922151656088943Down-regulated
137E030030I06RikTBTFemale20Weeksliver-0.926614679326768Down-regulated
138Gm3531TBTFemale20Weeksliver-0.931335142051227Down-regulated
139Slc16a13TBTFemale20Weeksliver-0.939253393076081Down-regulated
140Gm16793TBTFemale20Weeksliver-0.947858507126715Down-regulated
141Gm10443TBTFemale20Weeksliver-0.960780199110094Down-regulated
142PpardTBTFemale20Weeksliver-0.968261868270136Down-regulated
143Slc45a3TBTFemale20Weeksliver-0.978042578363119Down-regulated
144Disp2TBTFemale20Weeksliver-0.982347821691133Down-regulated
145Acss2TBTFemale20Weeksliver-0.985859448702771Down-regulated
146GckTBTFemale20Weeksliver-0.989460924129743Down-regulated
147Chac1TBTFemale20Weeksliver-0.990643959390708Down-regulated
148Rgs3TBTFemale20Weeksliver-0.997541484908891Down-regulated
149Tiam2TBTFemale20Weeksliver-1.00528127974345Down-regulated
150Gm6135TBTFemale20Weeksliver-1.00752875581098Down-regulated
151Gm13341TBTFemale20Weeksliver-1.01035668340502Down-regulated
152Mup2TBTFemale20Weeksliver-1.0184045382382Down-regulated
153Creld2TBTFemale20Weeksliver-1.01865558234573Down-regulated
154Gm3219TBTFemale20Weeksliver-1.02049244892131Down-regulated
155Mup14TBTFemale20Weeksliver-1.02611289907227Down-regulated
156Mir703TBTFemale20Weeksliver-1.03834824560553Down-regulated
1574930579G24RikTBTFemale20Weeksliver-1.04255592096676Down-regulated
158Gm13775TBTFemale20Weeksliver-1.05099432844237Down-regulated
159Gm4129TBTFemale20Weeksliver-1.08591413812508Down-regulated
160Spry4TBTFemale20Weeksliver-1.08631673903393Down-regulated
161Fabp5TBTFemale20Weeksliver-1.09822055353231Down-regulated
162CcnfTBTFemale20Weeksliver-1.13139844775732Down-regulated
163Gm10039TBTFemale20Weeksliver-1.13835013510685Down-regulated
164Gm11967TBTFemale20Weeksliver-1.15886798788585Down-regulated
165Gm10053TBTFemale20Weeksliver-1.16199568668931Down-regulated
166Gm16551TBTFemale20Weeksliver-1.16881837235792Down-regulated
167Unc79TBTFemale20Weeksliver-1.1762739583724Down-regulated
168TskuTBTFemale20Weeksliver-1.19084157634671Down-regulated
169Elovl3TBTFemale20Weeksliver-1.19242612971275Down-regulated
170Sult5a1TBTFemale20Weeksliver-1.19342744377137Down-regulated
171Gm48878TBTFemale20Weeksliver-1.1940403333638Down-regulated
172Cry1TBTFemale20Weeksliver-1.25064869330434Down-regulated
173AA986860TBTFemale20Weeksliver-1.2519825849563Down-regulated
174Gm32872TBTFemale20Weeksliver-1.25345176328437Down-regulated
175Rsph4aTBTFemale20Weeksliver-1.25442453914052Down-regulated
176MthfrTBTFemale20Weeksliver-1.26219854343541Down-regulated
177Slc25a30TBTFemale20Weeksliver-1.28658843543494Down-regulated
178Mup19TBTFemale20Weeksliver-1.33963924288205Down-regulated
179Gm38832TBTFemale20Weeksliver-1.35331008940012Down-regulated
180Ugt2b37TBTFemale20Weeksliver-1.3656939850589Down-regulated
181Serpina12TBTFemale20Weeksliver-1.39417313642393Down-regulated
1823930402G23RikTBTFemale20Weeksliver-1.39663519802523Down-regulated
183Cadm4TBTFemale20Weeksliver-1.42345223117576Down-regulated
184Gm42418TBTFemale20Weeksliver-1.43993886721804Down-regulated
185Loxl4TBTFemale20Weeksliver-1.45094207873771Down-regulated
186Srgap3TBTFemale20Weeksliver-1.4589278721137Down-regulated
187Zbtb16TBTFemale20Weeksliver-1.47910243085039Down-regulated
188Gm25911TBTFemale20Weeksliver-1.506300665569Down-regulated
189Pnpla3TBTFemale20Weeksliver-1.51088000056863Down-regulated
190Nr0b2TBTFemale20Weeksliver-1.51734297321026Down-regulated
191Mir6236TBTFemale20Weeksliver-1.53508922488858Down-regulated
192Gm15564TBTFemale20Weeksliver-1.57732249893429Down-regulated
193Npas2TBTFemale20Weeksliver-1.65644789335725Down-regulated
194Egr1TBTFemale20Weeksliver-1.67899197832086Down-regulated
195Sult3a2TBTFemale20Weeksliver-1.69826053463834Down-regulated
196Cyp3a16TBTFemale20Weeksliver-1.71559144666161Down-regulated
197Lpin1TBTFemale20Weeksliver-1.71963713930298Down-regulated
198Akr1c18TBTFemale20Weeksliver-1.80021529590166Down-regulated
199Adcy1TBTFemale20Weeksliver-1.81366932537784Down-regulated
200n-R5-8s1TBTFemale20Weeksliver-1.82526478279335Down-regulated
201Cyp2c54TBTFemale20Weeksliver-1.83314897080386Down-regulated
202DctTBTFemale20Weeksliver-1.84080694411376Down-regulated
203Cd163TBTFemale20Weeksliver-1.85477661187114Down-regulated
204Cdkn1aTBTFemale20Weeksliver-1.89694677008175Down-regulated
205Mup16TBTFemale20Weeksliver-2.00378627521583Down-regulated
206Cyp3a41bTBTFemale20Weeksliver-2.02308774384056Down-regulated
207Cyp3a44TBTFemale20Weeksliver-2.29342174449393Down-regulated
208Serpina4-ps1TBTFemale20Weeksliver-2.48644301325284Down-regulated
209Mup15TBTFemale20Weeksliver-2.51473711254973Down-regulated
210Mup18TBTFemale20Weeksliver-2.54160850069319Down-regulated
211Gm21320TBTFemale20Weeksliver-2.69416966003727Down-regulated
212Mup17TBTFemale20Weeksliver-2.76937600744017Down-regulated
213Hsd3b5TBTFemale20Weeksliver-2.79666367003857Down-regulated
214Sult3a1TBTFemale20Weeksliver-2.86119599863617Down-regulated
215Slco1a1TBTFemale20Weeksliver-2.99271574539738Down-regulated