ToxiTaRGET Database of Toxicant Exposures and Response
As BPA10mg BPA10ug DEHP Pb PM2.5(JHK) PM2.5(CHI) TBT TCDD


Table1. Number of differentially up-regulated gene in 20 weeks male liver under TBT exposure.
No.GeneExposureSexAgeTissueFold-changeDEG
1Clec2hTBTMale20Weeksliver3.51707800176734Up-regulated
2Pls1TBTMale20Weeksliver3.29702257590425Up-regulated
3Cyp7a1TBTMale20Weeksliver2.7074075134019Up-regulated
4Lgals4TBTMale20Weeksliver2.67154420741622Up-regulated
5Gsta1TBTMale20Weeksliver2.4773239480758Up-regulated
6Per3TBTMale20Weeksliver2.41962876604036Up-regulated
7DbpTBTMale20Weeksliver2.29163728546311Up-regulated
8Acot3TBTMale20Weeksliver2.21927048275374Up-regulated
9Serpinb1aTBTMale20Weeksliver2.15949246744346Up-regulated
10IgkcTBTMale20Weeksliver2.10151374987266Up-regulated
11Bhlhe41TBTMale20Weeksliver2.09449062095641Up-regulated
12Tmc4TBTMale20Weeksliver2.0368051220416Up-regulated
13AceTBTMale20Weeksliver2.0316944941486Up-regulated
14IhhTBTMale20Weeksliver1.81082447948076Up-regulated
15Upp2TBTMale20Weeksliver1.75369948595449Up-regulated
16Usp2TBTMale20Weeksliver1.74271107577924Up-regulated
17Wee1TBTMale20Weeksliver1.67384931506821Up-regulated
18Tspan8TBTMale20Weeksliver1.63032075197219Up-regulated
19Clic5TBTMale20Weeksliver1.59262734526933Up-regulated
20Pcsk4TBTMale20Weeksliver1.45909264117285Up-regulated
21PycardTBTMale20Weeksliver1.45487045195805Up-regulated
22EsrrgTBTMale20Weeksliver1.42090274865103Up-regulated
23Cyp2a5TBTMale20Weeksliver1.38757821969153Up-regulated
24EzrTBTMale20Weeksliver1.38577728861258Up-regulated
25Dpep1TBTMale20Weeksliver1.36804642783196Up-regulated
26Crip1TBTMale20Weeksliver1.3614216802789Up-regulated
27HpgdTBTMale20Weeksliver1.34023627988589Up-regulated
28TefTBTMale20Weeksliver1.33822537407592Up-regulated
29Slc39a5TBTMale20Weeksliver1.32163437895787Up-regulated
30Itpr3TBTMale20Weeksliver1.28924043351679Up-regulated
31Dclk3TBTMale20Weeksliver1.2635348666095Up-regulated
32Snhg11TBTMale20Weeksliver1.25781371237913Up-regulated
33Erbb2TBTMale20Weeksliver1.25551067411275Up-regulated
34CkbTBTMale20Weeksliver1.22571125092194Up-regulated
35Hsd3b2TBTMale20Weeksliver1.22061448372792Up-regulated
36Fam13aTBTMale20Weeksliver1.22053915294642Up-regulated
37Dsg1cTBTMale20Weeksliver1.2172295569859Up-regulated
38Gbp2bTBTMale20Weeksliver1.21383155228829Up-regulated
39Slc2a5TBTMale20Weeksliver1.20541147088916Up-regulated
40NrepTBTMale20Weeksliver1.18364699103343Up-regulated
41PkmTBTMale20Weeksliver1.17296225905924Up-regulated
42Nr1i3TBTMale20Weeksliver1.15961846539553Up-regulated
43Adamts7TBTMale20Weeksliver1.15054475232325Up-regulated
44A530020G20RikTBTMale20Weeksliver1.10090048349172Up-regulated
45RflnbTBTMale20Weeksliver1.09275684539282Up-regulated
46Abcb1aTBTMale20Weeksliver1.09087089476206Up-regulated
47Arhgef16TBTMale20Weeksliver1.09063078689897Up-regulated
48Gm21049TBTMale20Weeksliver1.08616982345964Up-regulated
49Lrrc8bTBTMale20Weeksliver1.08187984910114Up-regulated
50Grem2TBTMale20Weeksliver1.07828375599721Up-regulated
51MmeTBTMale20Weeksliver1.06557032926535Up-regulated
52Mical1TBTMale20Weeksliver1.05499677733043Up-regulated
53Ccdc73TBTMale20Weeksliver1.05462891517166Up-regulated
54Dok4TBTMale20Weeksliver1.05308291981752Up-regulated
55Tnfrsf19TBTMale20Weeksliver1.05007066743632Up-regulated
56Slco1a4TBTMale20Weeksliver1.04803625167599Up-regulated
57Naip6TBTMale20Weeksliver1.04142737633135Up-regulated
58Ccne2TBTMale20Weeksliver1.02625441534947Up-regulated
59NgefTBTMale20Weeksliver1.01223010647783Up-regulated
60St3gal6TBTMale20Weeksliver1.00903720791944Up-regulated
61Per2TBTMale20Weeksliver1.00835870848446Up-regulated
62Map2k6TBTMale20Weeksliver1.00758504071998Up-regulated
63BmfTBTMale20Weeksliver1.00753756424835Up-regulated
64Tk1TBTMale20Weeksliver0.978192469683687Up-regulated
65Abcd2TBTMale20Weeksliver0.977547243072805Up-regulated
66Sult1c2TBTMale20Weeksliver0.976610204103826Up-regulated
67Cyp46a1TBTMale20Weeksliver0.974858815915893Up-regulated
68Akr1c19TBTMale20Weeksliver0.967140106179437Up-regulated
69Fnip2TBTMale20Weeksliver0.949204293348892Up-regulated
70TrehTBTMale20Weeksliver0.945977633958912Up-regulated
71Kcnq1TBTMale20Weeksliver0.939589061695814Up-regulated
72Gm26684TBTMale20Weeksliver0.933377558204222Up-regulated
73Ugt1a6aTBTMale20Weeksliver0.917154413503978Up-regulated
74Akr1c14TBTMale20Weeksliver0.908639289491047Up-regulated
75Gm18635TBTMale20Weeksliver0.907409681955651Up-regulated
76C330021F23RikTBTMale20Weeksliver0.906865664020868Up-regulated
77Oxct1TBTMale20Weeksliver0.902772696804319Up-regulated
78Ank3TBTMale20Weeksliver0.899538331400534Up-regulated
79TnikTBTMale20Weeksliver0.890071114076325Up-regulated
802210039B01RikTBTMale20Weeksliver0.882551606922191Up-regulated
81Me2TBTMale20Weeksliver0.876789120612354Up-regulated
82MaoaTBTMale20Weeksliver0.876547517680407Up-regulated
83Rnf43TBTMale20Weeksliver0.873572909635409Up-regulated
84PfkpTBTMale20Weeksliver0.861224691074215Up-regulated
85Nr3c2TBTMale20Weeksliver0.858000462887165Up-regulated
86Tmtc4TBTMale20Weeksliver0.856470316150327Up-regulated
87Rps6ka5TBTMale20Weeksliver0.851627928200685Up-regulated
88Tspan13TBTMale20Weeksliver0.851624550284074Up-regulated
89Gm47528TBTMale20Weeksliver0.850976574922913Up-regulated
90Neat1TBTMale20Weeksliver0.85093042687031Up-regulated
91Cyp2e1TBTMale20Weeksliver0.846101894521559Up-regulated
92Ptgr1TBTMale20Weeksliver0.844352173366773Up-regulated
93Col27a1TBTMale20Weeksliver0.842633401329673Up-regulated
94Clec9aTBTMale20Weeksliver0.840992021677854Up-regulated
956720427I07RikTBTMale20Weeksliver0.839014899794863Up-regulated
96Slc16a12TBTMale20Weeksliver0.838905682592109Up-regulated
97Gm45250TBTMale20Weeksliver0.833481713092386Up-regulated
98A930033H14RikTBTMale20Weeksliver0.830389866323176Up-regulated
99Gm14305TBTMale20Weeksliver0.830052417587347Up-regulated
100Slc2a2TBTMale20Weeksliver0.825519133495374Up-regulated
101TertTBTMale20Weeksliver0.824450777757636Up-regulated
102Pde4bTBTMale20Weeksliver0.821833240102893Up-regulated
103Cyp2c54TBTMale20Weeksliver0.821785495868752Up-regulated
104Apol7aTBTMale20Weeksliver0.820498915046381Up-regulated
105Myh11TBTMale20Weeksliver0.813738064578268Up-regulated
106Ppp1r1bTBTMale20Weeksliver0.811841855273926Up-regulated
107Acot11TBTMale20Weeksliver0.811227798317213Up-regulated
108Azin2TBTMale20Weeksliver0.808722422714409Up-regulated
109Rps6ka1TBTMale20Weeksliver0.804022382339197Up-regulated
110Slc46a3TBTMale20Weeksliver0.799545800079499Up-regulated
111Cyp2c50TBTMale20Weeksliver0.797833771051631Up-regulated
112Ccdc34TBTMale20Weeksliver0.795580904328649Up-regulated
113TrhdeTBTMale20Weeksliver0.795290117000998Up-regulated
114Ccdc88cTBTMale20Weeksliver0.794479850347716Up-regulated
115Slc40a1TBTMale20Weeksliver0.791664448914831Up-regulated
116Slc6a8TBTMale20Weeksliver0.787944426913547Up-regulated
117Casp1TBTMale20Weeksliver0.780744126296723Up-regulated
118Tnfsf10TBTMale20Weeksliver0.780728132191039Up-regulated
119Slc37a2TBTMale20Weeksliver0.778862891672163Up-regulated
1205033421B08RikTBTMale20Weeksliver0.776626002564731Up-regulated
121Fam129bTBTMale20Weeksliver0.775004020512421Up-regulated
122Fgfrl1TBTMale20Weeksliver0.773594122123778Up-regulated
123Sucnr1TBTMale20Weeksliver0.771591806716699Up-regulated
124D130043K22RikTBTMale20Weeksliver0.770607392389069Up-regulated
125Gm4756TBTMale20Weeksliver0.769875513351953Up-regulated
126Nr1d2TBTMale20Weeksliver0.768009889025934Up-regulated
127Myo1dTBTMale20Weeksliver0.76703033608409Up-regulated
128Ankrd13bTBTMale20Weeksliver0.766147075034201Up-regulated
129Fzd8TBTMale20Weeksliver0.765232394642463Up-regulated
130Malat1TBTMale20Weeksliver0.762491021175965Up-regulated
131ScaiTBTMale20Weeksliver0.753733169023021Up-regulated
132Usp28TBTMale20Weeksliver0.75199987977593Up-regulated
133Adamdec1TBTMale20Weeksliver0.749973520487771Up-regulated
134Zfp970TBTMale20Weeksliver0.749509954336618Up-regulated
135Slc25a36TBTMale20Weeksliver0.746976659445054Up-regulated
136Cc2d2aTBTMale20Weeksliver0.740159945277635Up-regulated
137Gm17690TBTMale20Weeksliver0.739033539115806Up-regulated
138Brip1TBTMale20Weeksliver0.733393055222226Up-regulated
139AC163032.1TBTMale20Weeksliver0.730050518240476Up-regulated
140GmnnTBTMale20Weeksliver0.729509409088111Up-regulated
141Slco1b2TBTMale20Weeksliver0.727619814985566Up-regulated
142Neurl3TBTMale20Weeksliver0.72717463693901Up-regulated
143Aifm3TBTMale20Weeksliver0.723885300396804Up-regulated
144GlsTBTMale20Weeksliver0.722091215887973Up-regulated
145ToxTBTMale20Weeksliver0.721822173488233Up-regulated
146Sult1b1TBTMale20Weeksliver0.716822746258349Up-regulated
147Lpar2TBTMale20Weeksliver0.715686927938226Up-regulated
148Gm45051TBTMale20Weeksliver0.714160101073002Up-regulated
149SrcTBTMale20Weeksliver0.713960526004376Up-regulated
150Hsd3b3TBTMale20Weeksliver0.713902706220767Up-regulated
151Ankrd12TBTMale20Weeksliver0.713437474827115Up-regulated
152Il15TBTMale20Weeksliver0.708961497818685Up-regulated
153Arhgap6TBTMale20Weeksliver0.705680780718797Up-regulated
154Sort1TBTMale20Weeksliver0.702895003697107Up-regulated
155Gm14410TBTMale20Weeksliver0.702824577203314Up-regulated
156Golm1TBTMale20Weeksliver0.699904386401501Up-regulated
157Zswim9TBTMale20Weeksliver0.695301528173993Up-regulated
158Arrdc1TBTMale20Weeksliver0.694391745196969Up-regulated
1594632404H12RikTBTMale20Weeksliver0.691281063197866Up-regulated
160Lig1TBTMale20Weeksliver0.690572283562379Up-regulated
161Ddr1TBTMale20Weeksliver0.688862996888405Up-regulated
162Nr2f2TBTMale20Weeksliver0.680966096777435Up-regulated
163Chac2TBTMale20Weeksliver0.679053532785421Up-regulated
164OgtTBTMale20Weeksliver0.678855057987687Up-regulated
165Cdca3TBTMale20Weeksliver0.67830918380478Up-regulated
166Prss8TBTMale20Weeksliver0.67660432009612Up-regulated
167Limd2TBTMale20Weeksliver0.676453571147897Up-regulated
168Cd24aTBTMale20Weeksliver0.675941996876632Up-regulated
169Jade1TBTMale20Weeksliver0.674076259325313Up-regulated
170ItpkaTBTMale20Weeksliver0.673628933778548Up-regulated
171Ugp2TBTMale20Weeksliver0.672580984323233Up-regulated
172Acsm5TBTMale20Weeksliver0.67191994252483Up-regulated
173SordTBTMale20Weeksliver0.66949315673036Up-regulated
174Car1TBTMale20Weeksliver0.669371401575324Up-regulated
175Cfap20TBTMale20Weeksliver0.669364373594279Up-regulated
176Dvl2TBTMale20Weeksliver0.668493125837993Up-regulated
177InmtTBTMale20Weeksliver0.666551324734229Up-regulated
178NamptTBTMale20Weeksliver0.663384641977721Up-regulated
179Gm14403TBTMale20Weeksliver0.663237395664526Up-regulated
180Eef2kTBTMale20Weeksliver0.662602682251016Up-regulated
181Cyp2c37TBTMale20Weeksliver0.661231909347822Up-regulated
182Adcy6TBTMale20Weeksliver0.661055223588273Up-regulated
183Gm14325TBTMale20Weeksliver0.658301359739245Up-regulated
184Rab27bTBTMale20Weeksliver0.65206062572172Up-regulated
185Gys2TBTMale20Weeksliver0.651987030216612Up-regulated
186Shank2TBTMale20Weeksliver0.650753031825006Up-regulated
187HjurpTBTMale20Weeksliver0.645517743702331Up-regulated
188Plcb3TBTMale20Weeksliver0.645079298960323Up-regulated
189Nxpe2TBTMale20Weeksliver0.645050807696537Up-regulated
190AC135964.2TBTMale20Weeksliver0.644170518505562Up-regulated
191Dsc2TBTMale20Weeksliver0.642172257130353Up-regulated
192HyiTBTMale20Weeksliver0.641265517001471Up-regulated
193Ces1dTBTMale20Weeksliver0.638924949441081Up-regulated
194Ccdc68TBTMale20Weeksliver0.63442709323065Up-regulated
195Slc16a7TBTMale20Weeksliver0.634296773015558Up-regulated
196ArTBTMale20Weeksliver0.632460572246322Up-regulated
197EdaTBTMale20Weeksliver0.63088903255878Up-regulated
198Zfp971TBTMale20Weeksliver0.630804510656481Up-regulated
199PtgfrnTBTMale20Weeksliver0.630544720781656Up-regulated
200PlgrktTBTMale20Weeksliver0.630317868659139Up-regulated
201Serpina6TBTMale20Weeksliver0.625422990270177Up-regulated
202Gstt2TBTMale20Weeksliver0.621577665084331Up-regulated
203Car8TBTMale20Weeksliver0.620421154370459Up-regulated
204Naip5TBTMale20Weeksliver0.620268951921252Up-regulated
205Hdac11TBTMale20Weeksliver0.619105998290684Up-regulated
206BC024139TBTMale20Weeksliver0.617021560178425Up-regulated
207PdiltTBTMale20Weeksliver0.616076227801179Up-regulated
208E2f1TBTMale20Weeksliver0.60917596741727Up-regulated
209Snx32TBTMale20Weeksliver0.605417125452752Up-regulated
210Nox4TBTMale20Weeksliver0.604274319165283Up-regulated
211Fabp1TBTMale20Weeksliver0.603484496600277Up-regulated
212Fn3kTBTMale20Weeksliver0.602650296985293Up-regulated
213Cyp2c29TBTMale20Weeksliver0.601882071056848Up-regulated
214Lrrc45TBTMale20Weeksliver0.599764694681915Up-regulated
215Rbm47TBTMale20Weeksliver0.599099391876089Up-regulated
216Rufy3TBTMale20Weeksliver0.597770144529258Up-regulated
2175830473C10RikTBTMale20Weeksliver0.597595775366695Up-regulated
218Proser3TBTMale20Weeksliver0.59747380950504Up-regulated
219Ddb2TBTMale20Weeksliver0.597367944011698Up-regulated
220Naaladl2TBTMale20Weeksliver0.596133486798139Up-regulated
221Prkd3TBTMale20Weeksliver0.595339255464853Up-regulated
222Tcea3TBTMale20Weeksliver0.592453933908804Up-regulated
223Enpp2TBTMale20Weeksliver0.591881342195574Up-regulated
224RorcTBTMale20Weeksliver0.590559707491998Up-regulated
2251810059H22RikTBTMale20Weeksliver0.590497434066601Up-regulated
226Adh1TBTMale20Weeksliver0.59046670720264Up-regulated
227Akr1d1TBTMale20Weeksliver0.59035026062271Up-regulated
228Hook2TBTMale20Weeksliver0.589662104743098Up-regulated
229GhrTBTMale20Weeksliver0.588602616831546Up-regulated
230Ugt2b35TBTMale20Weeksliver0.587968143057832Up-regulated