ToxiTaRGET

As BPA10mg BPA10ug DEHP Pb PM2.5(JHK) PM2.5(CHI) TBT TCDD

Table1. Number of differentially down-regulated gene in 20 weeks male liver under Pb exposure.

No.	Gene	Exposure	Sex	Age	Tissue	Fold-change	DEG
1	Csad	Pb	Male	20Weeks	liver	-0.58509927586701	Down-regulated
2	Tmem132e	Pb	Male	20Weeks	liver	-0.585564209842156	Down-regulated
3	Armcx1	Pb	Male	20Weeks	liver	-0.585850787720516	Down-regulated
4	Bcap29	Pb	Male	20Weeks	liver	-0.590483121638626	Down-regulated
5	Rarres1	Pb	Male	20Weeks	liver	-0.593754527752726	Down-regulated
6	Gm13443	Pb	Male	20Weeks	liver	-0.599195237198167	Down-regulated
7	Gas7	Pb	Male	20Weeks	liver	-0.601770686380291	Down-regulated
8	Aen	Pb	Male	20Weeks	liver	-0.605528121929656	Down-regulated
9	Axin2	Pb	Male	20Weeks	liver	-0.605834486579744	Down-regulated
10	Dock2	Pb	Male	20Weeks	liver	-0.606354205587198	Down-regulated
11	Brca2	Pb	Male	20Weeks	liver	-0.607372383794651	Down-regulated
12	Enpp6	Pb	Male	20Weeks	liver	-0.608386240702274	Down-regulated
13	Gimap1	Pb	Male	20Weeks	liver	-0.611413090923681	Down-regulated
14	Mreg	Pb	Male	20Weeks	liver	-0.611867555024529	Down-regulated
15	Utp14b	Pb	Male	20Weeks	liver	-0.612393923958596	Down-regulated
16	Arhgap24	Pb	Male	20Weeks	liver	-0.619142552504351	Down-regulated
17	Nup160	Pb	Male	20Weeks	liver	-0.620115316412493	Down-regulated
18	Naf1	Pb	Male	20Weeks	liver	-0.622612902580388	Down-regulated
19	Ahr	Pb	Male	20Weeks	liver	-0.625495537274749	Down-regulated
20	Apoc2	Pb	Male	20Weeks	liver	-0.629607607847295	Down-regulated
21	Armcx5	Pb	Male	20Weeks	liver	-0.630693928516018	Down-regulated
22	Bend7	Pb	Male	20Weeks	liver	-0.63869035037991	Down-regulated
23	Ncoa4	Pb	Male	20Weeks	liver	-0.639309353259124	Down-regulated
24	Zscan25	Pb	Male	20Weeks	liver	-0.639854284363188	Down-regulated
25	Ap4e1	Pb	Male	20Weeks	liver	-0.641217491037159	Down-regulated
26	Slc25a53	Pb	Male	20Weeks	liver	-0.642563177629946	Down-regulated
27	mt-Co1	Pb	Male	20Weeks	liver	-0.642812216240955	Down-regulated
28	Fam208b	Pb	Male	20Weeks	liver	-0.645489233089424	Down-regulated
29	Plau	Pb	Male	20Weeks	liver	-0.646257553374073	Down-regulated
30	Oxct1	Pb	Male	20Weeks	liver	-0.648938646693676	Down-regulated
31	Ccdc77	Pb	Male	20Weeks	liver	-0.650015302757477	Down-regulated
32	Sorbs1	Pb	Male	20Weeks	liver	-0.65053824484185	Down-regulated
33	Gm39469	Pb	Male	20Weeks	liver	-0.656076748411547	Down-regulated
34	A1cf	Pb	Male	20Weeks	liver	-0.65834766989762	Down-regulated
35	Gas2l3	Pb	Male	20Weeks	liver	-0.661067536135907	Down-regulated
36	Trmt9b	Pb	Male	20Weeks	liver	-0.6611173141747	Down-regulated
37	Cmtr2	Pb	Male	20Weeks	liver	-0.673585324698397	Down-regulated
38	Carmil1	Pb	Male	20Weeks	liver	-0.673594699606474	Down-regulated
39	Adcy7	Pb	Male	20Weeks	liver	-0.677100606757017	Down-regulated
40	Cyb561a3	Pb	Male	20Weeks	liver	-0.679801102739273	Down-regulated
41	Tymp	Pb	Male	20Weeks	liver	-0.681938604108658	Down-regulated
42	She	Pb	Male	20Weeks	liver	-0.685310076506765	Down-regulated
43	Ugt3a1	Pb	Male	20Weeks	liver	-0.688043461108661	Down-regulated
44	Frat2	Pb	Male	20Weeks	liver	-0.689153505745629	Down-regulated
45	Nr1i3	Pb	Male	20Weeks	liver	-0.693560352705064	Down-regulated
46	Sytl4	Pb	Male	20Weeks	liver	-0.697909412995146	Down-regulated
47	Tbx3os1	Pb	Male	20Weeks	liver	-0.700907228999432	Down-regulated
48	Anxa11	Pb	Male	20Weeks	liver	-0.706464936150168	Down-regulated
49	mt-Tm	Pb	Male	20Weeks	liver	-0.712495380631765	Down-regulated
50	Syne1	Pb	Male	20Weeks	liver	-0.712877497226488	Down-regulated
51	Cdon	Pb	Male	20Weeks	liver	-0.714237012321204	Down-regulated
52	Ankrd52	Pb	Male	20Weeks	liver	-0.714338311109299	Down-regulated
53	Usp42	Pb	Male	20Weeks	liver	-0.717246650530098	Down-regulated
54	8030462N17Rik	Pb	Male	20Weeks	liver	-0.71810516514303	Down-regulated
55	Hgf	Pb	Male	20Weeks	liver	-0.722505652484301	Down-regulated
56	Tmcc2	Pb	Male	20Weeks	liver	-0.72373266812856	Down-regulated
57	Zfp626	Pb	Male	20Weeks	liver	-0.72593674127441	Down-regulated
58	Tlr8	Pb	Male	20Weeks	liver	-0.73211218164159	Down-regulated
59	Zc3h11a	Pb	Male	20Weeks	liver	-0.735005110779867	Down-regulated
60	Gm5345	Pb	Male	20Weeks	liver	-0.737279927657834	Down-regulated
61	Cd84	Pb	Male	20Weeks	liver	-0.745031418401478	Down-regulated
62	Myo9a	Pb	Male	20Weeks	liver	-0.745277042930112	Down-regulated
63	BC028528	Pb	Male	20Weeks	liver	-0.749802674542409	Down-regulated
64	Cyp2c55	Pb	Male	20Weeks	liver	-0.752216957362131	Down-regulated
65	Tlr5	Pb	Male	20Weeks	liver	-0.753921107630325	Down-regulated
66	Ccr5	Pb	Male	20Weeks	liver	-0.759613614967907	Down-regulated
67	Tpm1	Pb	Male	20Weeks	liver	-0.764209743844211	Down-regulated
68	B430306N03Rik	Pb	Male	20Weeks	liver	-0.766439518547586	Down-regulated
69	Rybp	Pb	Male	20Weeks	liver	-0.767420881618159	Down-regulated
70	Zfp960	Pb	Male	20Weeks	liver	-0.767962785491671	Down-regulated
71	Ugt1a6a	Pb	Male	20Weeks	liver	-0.767970269584784	Down-regulated
72	Ugt1a1	Pb	Male	20Weeks	liver	-0.773551664687458	Down-regulated
73	Car3	Pb	Male	20Weeks	liver	-0.774530729487702	Down-regulated
74	Mug-ps1	Pb	Male	20Weeks	liver	-0.775236075279111	Down-regulated
75	Gm20939	Pb	Male	20Weeks	liver	-0.777969638312524	Down-regulated
76	Cd86	Pb	Male	20Weeks	liver	-0.778318140517952	Down-regulated
77	Ces1d	Pb	Male	20Weeks	liver	-0.785301360787767	Down-regulated
78	Pdgfc	Pb	Male	20Weeks	liver	-0.793635460331848	Down-regulated
79	E430024I08Rik	Pb	Male	20Weeks	liver	-0.794596767534831	Down-regulated
80	Gm4952	Pb	Male	20Weeks	liver	-0.796138145939622	Down-regulated
81	Ksr1	Pb	Male	20Weeks	liver	-0.797105293059901	Down-regulated
82	Gm6652	Pb	Male	20Weeks	liver	-0.799482580654215	Down-regulated
83	Lipg	Pb	Male	20Weeks	liver	-0.803851582526271	Down-regulated
84	Cyp4a32	Pb	Male	20Weeks	liver	-0.80423603573461	Down-regulated
85	Fam84b	Pb	Male	20Weeks	liver	-0.805413380175957	Down-regulated
86	Gm20684	Pb	Male	20Weeks	liver	-0.816786483695237	Down-regulated
87	Lgr5	Pb	Male	20Weeks	liver	-0.821737072005226	Down-regulated
88	Kantr	Pb	Male	20Weeks	liver	-0.822825550907856	Down-regulated
89	Gm45250	Pb	Male	20Weeks	liver	-0.824272882756047	Down-regulated
90	Glb1l	Pb	Male	20Weeks	liver	-0.826371771151223	Down-regulated
91	Tmem38a	Pb	Male	20Weeks	liver	-0.839673741580229	Down-regulated
92	Tbx3	Pb	Male	20Weeks	liver	-0.848045744150106	Down-regulated
93	Irak3	Pb	Male	20Weeks	liver	-0.852364881021765	Down-regulated
94	Plpp3	Pb	Male	20Weeks	liver	-0.85306669986711	Down-regulated
95	Cyp2d38-ps	Pb	Male	20Weeks	liver	-0.853156683376532	Down-regulated
96	Tead1	Pb	Male	20Weeks	liver	-0.853397026514835	Down-regulated
97	Ano1	Pb	Male	20Weeks	liver	-0.855169367273228	Down-regulated
98	Neb	Pb	Male	20Weeks	liver	-0.855569605282483	Down-regulated
99	Pdpr	Pb	Male	20Weeks	liver	-0.865892846007841	Down-regulated
100	Uggt2	Pb	Male	20Weeks	liver	-0.885615124848779	Down-regulated
101	Zc4h2	Pb	Male	20Weeks	liver	-0.890320321821863	Down-regulated
102	Zswim6	Pb	Male	20Weeks	liver	-0.895240899797393	Down-regulated
103	5830417I10Rik	Pb	Male	20Weeks	liver	-0.897542625634621	Down-regulated
104	Mgat4a	Pb	Male	20Weeks	liver	-0.90576882823468	Down-regulated
105	Adap2	Pb	Male	20Weeks	liver	-0.915114828274205	Down-regulated
106	Slfn9	Pb	Male	20Weeks	liver	-0.918891831089057	Down-regulated
107	Sell	Pb	Male	20Weeks	liver	-0.920757449187584	Down-regulated
108	Gm35570	Pb	Male	20Weeks	liver	-0.921210622631458	Down-regulated
109	Pik3r3	Pb	Male	20Weeks	liver	-0.921981351270692	Down-regulated
110	Adra1a	Pb	Male	20Weeks	liver	-0.922359106224396	Down-regulated
111	Aatk	Pb	Male	20Weeks	liver	-0.922699128701916	Down-regulated
112	Sema5b	Pb	Male	20Weeks	liver	-0.923924399828094	Down-regulated
113	Unc45b	Pb	Male	20Weeks	liver	-0.933195072031578	Down-regulated
114	Gm24336	Pb	Male	20Weeks	liver	-0.93791376441837	Down-regulated
115	Ugt1a6b	Pb	Male	20Weeks	liver	-0.943591656451063	Down-regulated
116	Med12	Pb	Male	20Weeks	liver	-0.95509840186871	Down-regulated
117	Tmed10-ps	Pb	Male	20Weeks	liver	-0.957444354264116	Down-regulated
118	Cerkl	Pb	Male	20Weeks	liver	-0.960959803712968	Down-regulated
119	Crocc	Pb	Male	20Weeks	liver	-0.961141086431823	Down-regulated
120	Cyyr1	Pb	Male	20Weeks	liver	-0.962443051121776	Down-regulated
121	mt-Nd5	Pb	Male	20Weeks	liver	-0.963612491172072	Down-regulated
122	Nos1ap	Pb	Male	20Weeks	liver	-0.979927997982302	Down-regulated
123	P2ry4	Pb	Male	20Weeks	liver	-0.986374757326973	Down-regulated
124	Gbp10	Pb	Male	20Weeks	liver	-0.993764477295355	Down-regulated
125	Atg9a	Pb	Male	20Weeks	liver	-0.996592313713395	Down-regulated
126	Zfp971	Pb	Male	20Weeks	liver	-1.00388898377954	Down-regulated
127	Gm9938	Pb	Male	20Weeks	liver	-1.00928543670239	Down-regulated
128	mt-Tl1	Pb	Male	20Weeks	liver	-1.01041356531131	Down-regulated
129	Cd300ld	Pb	Male	20Weeks	liver	-1.01159328958159	Down-regulated
130	9930111J21Rik2	Pb	Male	20Weeks	liver	-1.0219481980254	Down-regulated
131	Gm47467	Pb	Male	20Weeks	liver	-1.02330967298133	Down-regulated
132	Thbs1	Pb	Male	20Weeks	liver	-1.026633817529	Down-regulated
133	Gm22486	Pb	Male	20Weeks	liver	-1.02828987322862	Down-regulated
134	Ptpn13	Pb	Male	20Weeks	liver	-1.02939114152515	Down-regulated
135	Sspn	Pb	Male	20Weeks	liver	-1.04114147698465	Down-regulated
136	F830016B08Rik	Pb	Male	20Weeks	liver	-1.05019164799539	Down-regulated
137	Kif20a	Pb	Male	20Weeks	liver	-1.054592072521	Down-regulated
138	Gm13509	Pb	Male	20Weeks	liver	-1.05723879062699	Down-regulated
139	Cysltr1	Pb	Male	20Weeks	liver	-1.06155258435672	Down-regulated
140	Prdm11	Pb	Male	20Weeks	liver	-1.06880849473529	Down-regulated
141	Npl	Pb	Male	20Weeks	liver	-1.06949330151794	Down-regulated
142	Mup14	Pb	Male	20Weeks	liver	-1.07263637242955	Down-regulated
143	Ugt1a5	Pb	Male	20Weeks	liver	-1.07647519659302	Down-regulated
144	Gm43189	Pb	Male	20Weeks	liver	-1.07851668276989	Down-regulated
145	Nexn	Pb	Male	20Weeks	liver	-1.07913990623586	Down-regulated
146	Pdp1	Pb	Male	20Weeks	liver	-1.08837746462688	Down-regulated
147	Gm9826	Pb	Male	20Weeks	liver	-1.09476205445412	Down-regulated
148	Mup8	Pb	Male	20Weeks	liver	-1.11458466153786	Down-regulated
149	Gm8941	Pb	Male	20Weeks	liver	-1.11990132708979	Down-regulated
150	Gm10698	Pb	Male	20Weeks	liver	-1.13990730821686	Down-regulated
151	C730036E19Rik	Pb	Male	20Weeks	liver	-1.14839256632137	Down-regulated
152	Col4a5	Pb	Male	20Weeks	liver	-1.15020103482889	Down-regulated
153	Ddias	Pb	Male	20Weeks	liver	-1.1558773635579	Down-regulated
154	Adam19	Pb	Male	20Weeks	liver	-1.15695813838442	Down-regulated
155	Rab6b	Pb	Male	20Weeks	liver	-1.16710433416677	Down-regulated
156	Folr2	Pb	Male	20Weeks	liver	-1.17660262452599	Down-regulated
157	1810046K07Rik	Pb	Male	20Weeks	liver	-1.17801610278876	Down-regulated
158	Gm38394	Pb	Male	20Weeks	liver	-1.19365234947353	Down-regulated
159	Col27a1	Pb	Male	20Weeks	liver	-1.20002507748095	Down-regulated
160	Pkia	Pb	Male	20Weeks	liver	-1.20144124451909	Down-regulated
161	Dct	Pb	Male	20Weeks	liver	-1.21090731953349	Down-regulated
162	Got2-ps1	Pb	Male	20Weeks	liver	-1.21501943448361	Down-regulated
163	Thtpa	Pb	Male	20Weeks	liver	-1.23813368526589	Down-regulated
164	Slc25a4	Pb	Male	20Weeks	liver	-1.25991924248451	Down-regulated
165	Piezo2	Pb	Male	20Weeks	liver	-1.26816997582659	Down-regulated
166	Eno3	Pb	Male	20Weeks	liver	-1.31440028095442	Down-regulated
167	March3	Pb	Male	20Weeks	liver	-1.31806498234598	Down-regulated
168	Fan1	Pb	Male	20Weeks	liver	-1.32094734049259	Down-regulated
169	Gm7463	Pb	Male	20Weeks	liver	-1.33983236436968	Down-regulated
170	Rab36	Pb	Male	20Weeks	liver	-1.36699014344869	Down-regulated
171	Trim34a	Pb	Male	20Weeks	liver	-1.38838871138874	Down-regulated
172	Cyp2c40	Pb	Male	20Weeks	liver	-1.4485038315675	Down-regulated
173	Mup-ps20	Pb	Male	20Weeks	liver	-1.54962448032815	Down-regulated
174	Mup1	Pb	Male	20Weeks	liver	-1.56927655363662	Down-regulated
175	Kcnk1	Pb	Male	20Weeks	liver	-1.56998856552825	Down-regulated
176	Tpm2	Pb	Male	20Weeks	liver	-1.59864893777333	Down-regulated
177	Myom1	Pb	Male	20Weeks	liver	-1.61322651982708	Down-regulated
178	Gm43305	Pb	Male	20Weeks	liver	-1.67509167745346	Down-regulated
179	Cyp2c69	Pb	Male	20Weeks	liver	-1.70868698653813	Down-regulated
180	Cyp7a1	Pb	Male	20Weeks	liver	-1.76582157942396	Down-regulated
181	Mup15	Pb	Male	20Weeks	liver	-1.9408027434378	Down-regulated
182	Atp1a2	Pb	Male	20Weeks	liver	-2.00741099024028	Down-regulated
183	Gm32468	Pb	Male	20Weeks	liver	-2.02133040549475	Down-regulated
184	Esrrg	Pb	Male	20Weeks	liver	-2.05289001799144	Down-regulated
185	Mylpf	Pb	Male	20Weeks	liver	-2.78570131389566	Down-regulated
186	H19	Pb	Male	20Weeks	liver	-2.92820959398285	Down-regulated
187	Cfd	Pb	Male	20Weeks	liver	-3.00333739944439	Down-regulated
188	Pygm	Pb	Male	20Weeks	liver	-3.11405812497249	Down-regulated
189	Myl1	Pb	Male	20Weeks	liver	-5.0647662568525	Down-regulated
190	Tnni2	Pb	Male	20Weeks	liver	-5.20436452716944	Down-regulated
191	Pvalb	Pb	Male	20Weeks	liver	-5.49356205250832	Down-regulated
192	Atp2a1	Pb	Male	20Weeks	liver	-5.95114681580598	Down-regulated
193	Tnnc2	Pb	Male	20Weeks	liver	-5.96194305398903	Down-regulated
194	Ckm	Pb	Male	20Weeks	liver	-6.32419710802606	Down-regulated
195	Mb	Pb	Male	20Weeks	liver	-6.41224125910504	Down-regulated
196	Acta1	Pb	Male	20Weeks	liver	-6.43930333297403	Down-regulated
197	Myh4	Pb	Male	20Weeks	liver	-6.47639136442665	Down-regulated
198	Tnnt3	Pb	Male	20Weeks	liver	-6.55270965681332	Down-regulated